ID   RTH-149
AC   CVCL_3467
SY   RTH 149; RTH149; Rainbow Trout Hepatoma-149
DR   BTO; BTO:0002602
DR   CLO; CLO_0008898
DR   ATCC; CRL-1710
DR   Wikidata; Q54951407
RX   CelloPub=CLPUB00103;
RX   CelloPub=CLPUB00703;
RX   DOI=10.1016/S1873-0140(05)80005-0;
RX   DOI=10.3147/jsfp.15.193;
RX   DOI=10.3147/jsfp.28.27;
RX   DOI=10.3147/jsfp.30.23;
RX   PubMed=6542066;
RX   PubMed=8736390;
RX   PubMed=19002917;
RX   PubMed=20420918;
RX   PubMed=28374170;
RX   PubMed=32707879;
RX   PubMed=33053677;
RX   PubMed=34382581;
CC   Group: Fish cell line.
CC   Virology: Susceptible to infection by infectious haematopoetic necrosis virus (IHNV) and infectious pancreatic necrosis virus (IPNV) (CelloPub=CLPUB00703).
CC   Transformant: ChEBI; CHEBI:2504; Aflatoxin B1 (AFB1).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Epithelial cell; CL=CL_0000066.
DI   NCIt; C134573; Rainbow trout hepatoma
OX   NCBI_TaxID=8022; ! Oncorhynchus mykiss (Rainbow trout)
SX   Sex unspecified
AG   Adult
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 22
//
RX   CelloPub=CLPUB00103;
RA   Yoshimizu M., Kamei M., Dirakbusarakom S., Kimura T.;
RT   "Fish cell lines: susceptibility to salmonid viruses.";
RL   (In) Invertebrate and fish tissue culture; Kuroda Y., Kurstak E., Maramorosch K. (eds.); pp.207-217; Japan Sci. Soc.; Tokyo (1988).
//
RX   CelloPub=CLPUB00703;
RA   Philippon-Fried M.;
RT   "Partial characterization of six established salmonid cell lines.";
RL   Thesis MSc (1979), Oregon State University, United States.
//
RX   DOI=10.1016/S1873-0140(05)80005-0;
RA   Bols N.C., Dayeh V.R., Lee L.E.J., Schirmer K.;
RT   "Use of fish cell lines in the toxicology and ecotoxicology of fish.
RT   Piscine cell lines in environmental toxicology.";
RL   (In) Biochemistry and molecular biology of fishes, Vol. 6; Mommsen T.P., Moon T.W. (eds.); pp.43-84; Elsevier; Amsterdam (2005).
//
RX   DOI=10.3147/jsfp.15.193;
RA   Fryer J.L., McCain B.B., Leong J.-A.C.;
RT   "A cell line derived from rainbow trout (Salmo gairdneri) hepatoma.";
RL   Fish Pathol. 15:193-200(1981).
//
RX   DOI=10.3147/jsfp.28.27;
RA   Fernandez R.D., Yoshimizu M., Ezura Y., Kimura T.;
RT   "Comparative growth response of fish cell lines in different media,
RT   temperatures, and and sodium chloride concentrations.";
RL   Fish Pathol. 28:27-34(1993).
//
RX   DOI=10.3147/jsfp.30.23;
RA   Oh M.-J., Yoshimizu M., Kimura T., Ezura Y.;
RT   "A new virus isolated from salmonid fish.";
RL   Fish Pathol. 30:23-32(1995).
//
RX   PubMed=6542066; DOI=10.1007/BF02618871;
RA   Lannan C.N., Winton J.R., Fryer J.L.;
RT   "Fish cell lines: establishment and characterization of nine cell
RT   lines from salmonids.";
RL   In Vitro 20:671-676(1984).
//
RX   PubMed=8736390; DOI=10.1177/019262339602400310;
RA   Carter C.A., Ellington W.W., Van Beneden R.J.;
RT   "Confocal laser scanning microscopy of oncogene localization in
RT   rainbow trout cell lines derived from normal and tumor tissue.";
RL   Toxicol. Pathol. 24:339-345(1996).
//
RX   PubMed=19002917; DOI=10.1023/A:1020516804173;
RA   Perry G.M.L., McDonald G.J., Ferguson M.M., Ganassin R.C., Bols N.C.;
RT   "Characterization of rainbow trout cell lines using microsatellite DNA
RT   profiling.";
RL   Cytotechnology 37:143-151(2001).
//
RX   PubMed=20420918; DOI=10.1016/j.fsi.2010.04.007;
RA   Kawano A., Kales S.C., Fujiki K., DeWitte-Orr S.J., Dixon B.,
RA   Lee L.E.J., Bols N.C.;
RT   "A comparison of rainbow trout cell lines for their expression of the
RT   major histocompatibility complex genes and the induction of
RT   beta-2-microglobulin by dsRNA.";
RL   Fish Shellfish Immunol. 29:312-318(2010).
//
RX   PubMed=28374170; DOI=10.1007/s11626-017-0142-5;
RA   Bols N.C., Pham P.H., Dayeh V.R., Lee L.E.J.;
RT   "Invitromatics, invitrome, and invitroomics: introduction of three new
RT   terms for in vitro biology and illustration of their use with the cell
RT   lines from rainbow trout.";
RL   In Vitro Cell. Dev. Biol. Anim. 53:383-405(2017).
//
RX   PubMed=32707879; DOI=10.3390/cells9081754;
RA   Morin G., Pinel K., Dias K., Seiliez I., Beaumatin F.;
RT   "RTH-149 cell line, a useful tool to decipher molecular mechanisms
RT   related to fish nutrition.";
RL   Cells 9:1754.1-1754.17(2020).
//
RX   PubMed=33053677; DOI=10.3390/pathogens9100833;
RA   Pham P.H., Misk E., Papazotos F., Jones G., Polinski M.P.,
RA   Contador E., Russell S., Garver K.A., Lumsden J.S., Bols N.C.;
RT   "Screening of fish cell lines for piscine orthoreovirus-1 (PRV-1)
RT   amplification: identification of the non-supportive PRV-1 invitrome.";
RL   Pathogens 9:833.1-833.25(2020).
//
RX   PubMed=34382581; DOI=10.3354/dao03615;
RA   Ito T., Kamaishi T.;
RT   "Japanese amberjack Seriola quinqueradiata and red sea bream Pagrus
RT   major susceptibility to infectious hematopoietic necrosis virus (IHNV)
RT   isolate.";
RL   Dis. Aquat. Organ. 146:1-8(2021).
//