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Cellosaurus THP-1l (CVCL_3427)

[Text version]
Cell line name THP-1l
Synonyms THP-1 l
Accession CVCL_3427
Resource Identification Initiative To cite this cell line use: THP-1l (RRID:CVCL_3427)
Comments Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:2457; CSNK2A1 + HGNC; HGNC:13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line).
  • Gene fusion; HGNC; HGNC:7132; KMT2A + HGNC; HGNC:7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).
Disease Childhood acute monocytic leukemia (NCIt: C9163)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0006 (THP-1)
Sex of cell Male
Age at sampling 1Y
Category Cancer cell line
STR profile Source(s): ICLC=HTL05009

Markers:
AmelogeninX,Y
D8S117910,14
D18S5113,14
D21S1130,31.2
FGA24,25
TH018,9.3
vWA16

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Cross-references
Cell line collections (Providers) ICLC; HTL05009
Cell line databases/resources CLDB; cl7172
cancercelllines; CVCL_3427
Encyclopedic resources Wikidata; Q54972348
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21