ID   Lu-141
AC   CVCL_3347
SY   LU-141; Lu141
DR   CLO; CLO_0050070
DR   BioSample; SAMN03472075
DR   cancercelllines; CVCL_3347
DR   CGH-DB; 94-1
DR   CGH-DB; 9065-4
DR   Cosmic; 801609
DR   Cosmic; 809125
DR   Cosmic; 918009
DR   Cosmic; 929981
DR   IARC_TP53; 1019
DR   RCB; RCB1772
DR   Wikidata; Q54903202
RX   PubMed=1312700;
RX   PubMed=10536175;
RX   PubMed=12107105;
RX   PubMed=38639832;
CC   Population: Korean.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Unspecified (PubMed=1312700; PubMed=10536175).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
ST   Source(s): RCB=RCB1772
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D16S539: 9
ST   D5S818: 11,12
ST   D7S820: 11
ST   TH01: 9
ST   TPOX: 8
ST   vWA: 14,16
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   67Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 21
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RX   PubMed=1312700;
RA   Sameshima Y., Matsuno Y., Hirohashi S., Shimosato Y., Mizoguchi H.,
RA   Sugimura T., Terada M., Yokota J.;
RT   "Alterations of the p53 gene are common and critical events for the
RT   maintenance of malignant phenotypes in small-cell lung carcinoma.";
RL   Oncogene 7:451-457(1992).
//
RX   PubMed=10536175; DOI=10.3892/ijo.15.5.927;
RA   Fujita T., Kiyama M., Tomizawa Y., Kohno T., Yokota J.;
RT   "Comprehensive analysis of p53 gene mutation characteristics in lung
RT   carcinoma with special reference to histological subtypes.";
RL   Int. J. Oncol. 15:927-934(1999).
//
RX   PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7; PMCID=PMC1850681;
RA   Yokoi S., Yasui K., Saito-Ohara F., Koshikawa K., Iizasa T.,
RA   Fujisawa T., Terasaki T., Horii A., Takahashi T., Hirohashi S.,
RA   Inazawa J.;
RT   "A novel target gene, SKP2, within the 5p13 amplicon that is
RT   frequently detected in small cell lung cancers.";
RL   Am. J. Pathol. 161:207-216(2002).
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RX   PubMed=38639832; DOI=10.1007/s13577-024-01055-0; PMCID=PMC11194210;
RA   Kasai F., Fukushima M., Miyagi Y., Nakamura Y.;
RT   "Genetic diversity among the present Japanese population: evidence
RT   from genotyping of human cell lines established in Japan.";
RL   Hum. Cell 37:944-950(2024).
//