ID   ZFL
AC   CVCL_3276
SY   ZF-L; ZebraFish Liver; ZLE; Zebrafish Liver Epithelium
DR   CLO; CLO_0009725
DR   ATCC; CRL-2643
DR   BCRC; 60454
DR   BCRJ; 0256
DR   FCS-free; 154-27-282-1-4-3
DR   Wikidata; Q54995906
RX   DOI=10.1007/BF01404818;
RX   PubMed=7994634;
RX   PubMed=24355757;
RX   PubMed=25536407;
RX   PubMed=28587087;
CC   Group: Fish cell line.
CC   Doubling time: 2.54 +- 0.28 days (Note=In L-15-FBS), 6.6 +- 0.43 days (Note=In UltraMEM-ITES) (PubMed=28587087); 72 hours (ATCC=CRL-2643).
CC   Donor information: According to PubMed 7994634 obtained from pooling the livers of three fish, while ATCC mentions 10 individuals (ATCC=CRL-2643; PubMed=7994634).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Epithelial cell; CL=CL_0000066.
OX   NCBI_TaxID=7955; ! Danio rerio (Zebrafish)
SX   Sex unspecified
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 21
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RX   PubMed=28587087; DOI=10.3390/md15060147; PMCID=PMC5484097;
RA   Liu, Chieh-Lun
RA   Watson, Aaron M.
RA   Place, Allen R.
RA   Jagus, Rosemary
RT   "Taurine biosynthesis in a fish liver cell line (ZFL) adapted to a
RT   serum-free medium.";
RL   Mar. Drugs 15:147.1-147.15(2017).
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RX   PubMed=24355757; DOI=10.1016/j.aquatox.2013.11.023;
RA   Eide, Marta
RA   Rusten, Marte
RA   Male, Rune
RA   Jensen, Knut Helge Midtbo
RA   Goksoyr, Anders
RT   "A characterization of the ZFL cell line and primary hepatocytes as in
RT   vitro liver cell models for the zebrafish (Danio rerio).";
RL   Aquat. Toxicol. 147:7-17(2014).
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RX   PubMed=25536407; DOI=10.1016/j.cbpb.2014.12.002;
RA   Ruyra, Angels
RA   Torrealba, Debora
RA   Morera, Davinia
RA   Tort, Lluis
RA   MacKenzie, Simon
RA   Roher, Nerea
RT   "Zebrafish liver (ZFL) cells are able to mount an anti-viral response
RT   after stimulation with poly (I:C).";
RL   Comp. Biochem. Physiol. 182B:55-63(2015).
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RX   DOI=10.1007/BF01404818;
RA   Bradford, C. Samuel
RA   Sun, Le
RA   Collodi, Paul
RA   Barnes, David W.
RT   "Cell cultures from zebrafish embryos and adult tissues.";
RL   J. Tissue Cult. Methods 16:99-107(1994).
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RX   PubMed=7994634; DOI=10.1007/BF00757560;
RA   Ghosh, Chandramallika
RA   Zhou, Y.L.
RA   Collodi, Paul
RT   "Derivation and characterization of a zebrafish liver cell line.";
RL   Cell Biol. Toxicol. 10:167-176(1994).
//