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Cellosaurus UBE6T-7 (CVCL_3224)

[Text version]
Cell line name UBE6T-7
Synonyms UBET-7
Accession CVCL_3224
Resource Identification Initiative To cite this cell line use: UBE6T-7 (RRID:CVCL_3224)
Comments Population: Japanese and Korean.
Genetic integration: Method=Transduction; Gene=HGNC; 1066; BMI1.
Genetic integration: Method=Transduction; Gene=HGNC; 11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Mesenchymal stem cell of bone marrow; CL=CL_0002540.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6F32 (H4-1 [Human bone marrow])
Sex of cell Female
Age at sampling 91Y
Category Telomerase immortalized cell line
STR profile Source(s): JCRB=JCRB1143; RCB=RCB2157

Markers:
AmelogeninX
CSF1PO11,12
D5S81810,13
D7S8208,11
D13S3178
D16S53911,12
TH019
TPOX11
vWA17,18

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Publications

PubMed=15293342; DOI=10.1002/jgm.583
Takeda Y., Mori T., Imabayashi H., Kiyono T., Gojo S., Miyoshi S., Hida N., Ita M., Segawa K., Ogawa S., Sakamoto M., Nakamura S., Umezawa A.
Can the life span of human marrow stromal cells be prolonged by bmi-1, E6, E7, and/or telomerase without affecting cardiomyogenic differentiation?
J. Gene Med. 6:833-845(2004)

PubMed=15923633; DOI=10.1128/mcb.25.12.5183-5195.2005; PMCID=PMC1140572
Mori T., Kiyono T., Imabayashi H., Takeda Y., Tsuchiya K., Miyoshi S., Makino H., Matsumoto K., Saito H., Ogawa S., Sakamoto M., Hata J.-i., Umezawa A.
Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential.
Mol. Cell. Biol. 25:5183-5195(2005)

PubMed=21155951; DOI=10.1111/j.1365-2443.2010.01459.x
Toyoda M., Yamazaki-Inoue M., Itakura Y., Kuno A., Ogawa T., Yamada M., Akutsu H., Takahashi Y., Kanzaki S., Narimatsu H., Hirabayashi J., Umezawa A.
Lectin microarray analysis of pluripotent and multipotent stem cells.
Genes Cells 16:1-11(2011)

Cross-references
Cell line collections (Providers) JCRB; JCRB1143
JCRB; NIHS0451 - Discontinued
RCB; RCB2157 - Discontinued
Cell line databases/resources CLO; CLO_0051553
SKIP; SKIP000715
Biological sample resources BioSample; SAMN03472463
Encyclopedic resources Wikidata; Q54973893
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number20