ID   SAT [Human HNSCC]
AC   CVCL_3160
SY   Sat
DR   CLO; CLO_0009952
DR   ArrayExpress; E-MTAB-3610
DR   BioSample; SAMN03472538
DR   cancercelllines; CVCL_3160
DR   Cell_Model_Passport; SIDM00350
DR   Cosmic-CLP; 1299050
DR   DepMap; ACH-001641
DR   EGA; EGAS00001000978
DR   GDSC; 1299050
DR   GEO; GSM827190
DR   GEO; GSM1670403
DR   JCRB; JCRB1027
DR   JCRB; NIHS0257
DR   LINCS_LDP; LCL-1210
DR   PharmacoDB; SAT_1346_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_3160
DR   Wikidata; Q54952126
RX   PubMed=10601556;
RX   PubMed=20215515;
RX   PubMed=27397505;
RX   PubMed=30894373;
RX   PubMed=35839778;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Population: Japanese.
CC   Characteristics: Established from a nude mouse xenograft.
CC   Doubling time: 72 hours (PubMed=10601556).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Omics: Deep exome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Genome ancestry: African=0.32%; Native American=1.29%; East Asian, North=77.72%; East Asian, South=18.87%; South Asian=0%; European, North=1.81%; European, South=0% (PubMed=30894373).
CC   Discontinued: JCRB; NIHS0257; true.
ST   Source(s): Cosmic-CLP; DepMap; JCRB
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 10,12
ST   D16S539: 10,12
ST   D18S51: 18
ST   D21S11: 29,32.1
ST   D3S1358: 17
ST   D5S818: 13
ST   D7S820: 11,12
ST   D8S1179: 13,14
ST   FGA: 24
ST   Penta D: 8,13
ST   Penta E: 12
ST   TH01: 9
ST   TPOX: 9,11
ST   vWA: 14,18
DI   NCIt; C34447; Head and neck squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 28
//
RX   PubMed=10601556; DOI=10.3892/ijo.16.1.119;
RA   Nii M., Kayada Y., Yoshiga K., Takada K., Okamoto T., Yanagihara K.;
RT   "Suppression of metastasis by tissue inhibitor of metalloproteinase-1
RT   in a newly established human oral squamous cell carcinoma cell line.";
RL   Int. J. Oncol. 16:119-124(2000).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017;
RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
RA   Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X.,
RA   Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S.,
RA   Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P.,
RA   Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H.,
RA   Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.;
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010;
RA   Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N.,
RA   Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J.,
RA   Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L.,
RA   Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S.,
RA   Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B.,
RA   Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.;
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//