ID   PALL-2
AC   CVCL_3122
SY   PALL2; Ph1-positive Acute Lymphoblastic Leukemia-2
DR   JCRB; JCRB1345
DR   JCRB; NIHS0546
DR   SKIP; SKIP000748
DR   Wikidata; Q54937484
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=8428799;
RX   PubMed=10071072;
RX   PubMed=35124168;
CC   Population: Japanese.
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=8428799; PubMed=10071072).
CC   Sequence variation: Mutation; HGNC; HGNC:12766; NSD2; Simple; p.His554Gln (c.1662C>G); ClinVar=VCV001680176; Zygosity=Heterozygous (PubMed=35124168).
CC   Discontinued: JCRB; NIHS0546; true.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): JCRB=JCRB1345
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 8
ST   D16S539: 9,10
ST   D5S818: 11,12
ST   D7S820: 8,11
ST   TH01: 7,9
ST   TPOX: 8
ST   vWA: 18,19
DI   NCIt; C114819; Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
DI   ORDO; Orphanet_585909; B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   45Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 20
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=8428799; DOI=10.1002/ijc.2910530318;
RA   Miyagi T., Ohyashiki J.H., Yamato K., Koeffler H.P., Miyoshi I.;
RT   "Phenotypic and molecular analysis of Ph1-chromosome-positive acute
RT   lymphoblastic leukemia cell lines.";
RL   Int. J. Cancer 53:457-462(1993).
//
RX   PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4;
RA   Drexler H.G., MacLeod R.A.F., Uphoff C.C.;
RT   "Leukemia cell lines: in vitro models for the study of Philadelphia
RT   chromosome-positive leukemia.";
RL   Leuk. Res. 23:207-215(1999).
//
RX   PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068;
RA   Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C.,
RA   Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H.,
RA   Minegishi M., Iwamoto S., Sugita K., Inukai T.;
RT   "Glucocorticoid receptor gene mutations confer glucocorticoid
RT   resistance in B-cell precursor acute lymphoblastic leukemia.";
RL   J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022).
//