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Cellosaurus OCUG-1 (CVCL_3083)

[Text version]
Cell line name OCUG-1
Synonyms OCUG1; Osaka City University Gallbladder-1
Accession CVCL_3083
Resource Identification Initiative To cite this cell line use: OCUG-1 (RRID:CVCL_3083)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 47.1 hours (PubMed=21533512).
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Peritoneal effusion; UBERON=UBERON_0001268.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg267Trp (c.799C>T); ClinVar=VCV000141764; Zygosity=Heterozygous (DepMap=ACH-001619).
Disease Gallbladder carcinoma (NCIt: C3844)
Carcinoma of gallbladder and extrahepatic biliary tract (ORDO: Orphanet_56044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_XD21 (OCUG-1-Luc#5)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001619; JCRB=JCRB0191

Markers:
AmelogeninX
CSF1PO10,12
D3S135815
D5S81810,12
D7S82010,11
D8S117914,15
D13S3178,11
D16S5399,13
D18S5116,19
D21S1128,29
FGA21,24
Penta D9
Penta E5,20
TH017,9.3
TPOX8,11
vWA15,16 (JCRB=JCRB0191)
16 (DepMap=ACH-001619)

Run an STR similarity search on this cell line
Publications

PubMed=21533512; DOI=10.3892/ijo.10.6.1251
Yamada N., Chung Y.-S., Ohtani H., Ikeda T., Onoda N., Sawada T., Nishiguchi Y., Hasuma T., Sowa M.
Establishment and characterization of a new human gallbladder carcinoma cell line (OCUG-1) producing TA-4.
Int. J. Oncol. 10:1251-1255(1997)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=32899426; DOI=10.3390/cancers12092510; PMCID=PMC7565451
Scherer D., Davila-Lopez M., Goeppert B., Abrahamsson S., Gonzalez Silos R., Nova I., Marcelain K., Roa J.C., Ibberson D., Umu S.U., Rounge T.B., Roessler S., Lorenzo-Bermejo J.
RNA sequencing of hepatobiliary cancer cell lines: data and applications to mutational and transcriptomic profiling.
Cancers (Basel) 12:2510.1-2510.14(2020)

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vijay V., Karisani N., Shi L., Hung Y.-H., Vu P., Kattel P., Kenney L., Merritt J., Adil R., Wu Q.-B., Zhen Y.-L., Morris R., Kreuzer J., Kathiresan M., Herrera Lopez X.I., Ellis H., Gritti I.G., Lecorgne L., Farag I., Popa A., Shen W., Kato H., Xu Q., Balasooriya E.R., Wu M.-J., Chaturantabut S., Kelley R.K., Cleary J.M., Lawrence M.S., Root D.E., Benes C.H., Deshpande V., Juric D., Sellers W.R., Ferrone C.R., Haas W., Vazquez F., Getz G., Bardeesy N.M.
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line collections (Providers) JCRB; JCRB0191
Cell line databases/resources CLO; CLO_0009938
cancercelllines; CVCL_3083
Cell_Model_Passport; SIDM01842
DepMap; ACH-001619
LINCS_LDP; LCL-1800
Biological sample resources BioSample; SAMN03471651
Encyclopedic resources Wikidata; Q54931819
Gene expression databases GEO; GSM827176
Polymorphism and mutation databases Cosmic; 2629295
Cosmic; 2674062
Progenetix; CVCL_3083
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number26