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Cellosaurus MCF-7D3Res (CVCL_2Z98)

[Text version]
Cell line name MCF-7D3Res
Accession CVCL_2Z98
Resource Identification Initiative To cite this cell line use: MCF-7D3Res (RRID:CVCL_2Z98)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27300; Vitamin D.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=8593782; DOI=10.1210/endo.137.2.8593782
Narvaez C.J., Vanweelden K., Byrne I., Welsh J.
Characterization of a vitamin D3-resistant MCF-7 cell line.
Endocrinology 137:400-409(1996)

Cross-references
Cell line databases/resources cancercelllines; CVCL_2Z98
Encyclopedic resources Wikidata; Q54904405
Entry history
Entry creation22-Sep-2015
Last entry update05-Oct-2023
Version number14