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Cellosaurus CC20 [Human colon adenocarcinoma] (CVCL_2H54)

[Text version]
Cell line name CC20 [Human colon adenocarcinoma]
Accession CVCL_2H54
Resource Identification Initiative To cite this cell line use: CC20 [Human colon adenocarcinoma] (RRID:CVCL_2H54)
Comments Part of: AstraZeneca Colorectal cell line (AZCL) panel.
Omics: Deep proteome analysis.
Omics: Transcriptome analysis by microarray.
Sequence variations
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2H55 ! CC21 [Human colon adenocarcinoma]
CVCL_2H56 ! CC22
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2994902; DOI=10.1093/carcin/6.10.1533
Greenhalgh D.A., Kinsella A.R.
c-Ha-ras not c-Ki-ras activation in three colon tumour cell lines.
Carcinogenesis 6:1533-1535(1985)

PubMed=8464898; DOI=10.1073/pnas.90.7.2842
Browning M.J., Krausa P., Rowan A.J., Bicknell D.C., Bodmer J.G., Bodmer W.F.
Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.
Proc. Natl. Acad. Sci. U.S.A. 90:2842-2845(1993)

PubMed=16418264; DOI=10.1073/pnas.0510146103
Liu Y., Bodmer W.F.
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines.
Proc. Natl. Acad. Sci. U.S.A. 103:976-981(2006)

PubMed=18258742; DOI=10.1073/pnas.0712176105
Emaduddin M., Bicknell D.C., Bodmer W.F., Feller S.M.
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 105:2358-2362(2008)

PubMed=20606684; DOI=10.1038/sj.bjc.6605780
Bracht K., Nicholls A.M., Liu Y., Bodmer W.F.
5-fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.
Br. J. Cancer 103:340-346(2010)

PubMed=23272949; DOI=10.1186/1755-8794-5-66
Schlicker A., Beran G., Chresta C.M., McWalter G., Pritchard A., Weston S., Runswick S., Davenport S., Heathcote K., Castro D.A., Orphanides G., French T., Wessels L.F.A.
Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.
BMC Med. Genomics 5:66.1-66.15(2012)

PubMed=29101300; DOI=10.15252/msb.20177701
Frejno M., Zenezini Chiozzi R., Wilhelm M., Koch H., Zheng R.-S., Klaeger S., Ruprecht B., Meng C., Kramer K., Jarzab A., Heinzlmeir S., Johnstone E., Domingo E., Kerr D., Jesinghaus M., Slotta-Huspenina J., Weichert W., Knapp S., Feller S.M., Kuster B.
Pharmacoproteomic characterisation of human colon and rectal cancer.
Mol. Syst. Biol. 13:951-951(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_2H54
Encyclopedic resources Wikidata; Q54808730
Gene expression databases GEO; GSM1374442
Polymorphism and mutation databases Cosmic; 2760076
IARC_TP53; 21750
Proteomic databases PRIDE; PXD005354
PRIDE; PXD005355
Entry history
Entry creation22-Sep-2015
Last entry update05-Oct-2023
Version number14