ID   SRD-12B
AC   CVCL_2H51
SY   SRD12B; Sterol Regulatory Defective-12B
DR   Wikidata; Q54955656
RX   PubMed=9774448;
CC   Characteristics: Has a defect in the site 1 cleavage reaction.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 15455; MBTPS2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCIt; C129643; Cesium-137 gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_2H49 ! CHO/pS2P
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 22-09-15; Last updated: 10-09-24; Version: 9
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RX   PubMed=9774448; DOI=10.1074/jbc.273.43.28261;
RA   Rawson R.B., Cheng D., Brown M.S., Goldstein J.L.;
RT   "Isolation of cholesterol-requiring mutant Chinese hamster ovary cells
RT   with defects in cleavage of sterol regulatory element-binding proteins
RT   at site 1.";
RL   J. Biol. Chem. 273:28261-28269(1998).
//