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Cellosaurus AG04446 (CVCL_2A88)

[Text version]
Cell line name AG04446
Synonyms AG_04446; GRC#0246
Accession CVCL_2A88
Resource Identification Initiative To cite this cell line use: AG04446 (RRID:CVCL_2A88)
Comments Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection.
Population: Caucasian.
Senescence: Senesces at 37 PDL (PubMed=9724752); 33 PDL (Coriell=AG04446).
Doubling time: 2.2 days (PubMed=12840040).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2E80 ! AG12851
Sex of cell Male
Age at sampling 48Y
Category Finite cell line
Publications

PubMed=7307581; DOI=10.1159/000131624
Schneider E.L., Monticone R., Smith J.R., Braunschweiger K.I., Roberts T.W.
Skin fibroblast cultures derived from members of the Baltimore longitudinal study: a new resource for studies of cellular aging.
Cytogenet. Cell Genet. 31:40-46(1981)

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=9724752; DOI=10.1073/pnas.95.18.10614; PMCID=PMC27943
Cristofalo V.J., Allen R.G., Pignolo R.J., Martin B.G., Beck J.C.
Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation.
Proc. Natl. Acad. Sci. U.S.A. 95:10614-10619(1998)

PubMed=12840040; DOI=10.1101/gr.1289803; PMCID=PMC403735
Karaman M.W., Houck M.L., Chemnick L.G., Nagpal S., Chawannakul D., Sudano D., Pike B.L., Ho V.V., Ryder O.A., Hacia J.G.
Comparative analysis of gene-expression patterns in human and African great ape cultured fibroblasts.
Genome Res. 13:1619-1630(2003)

Cross-references
Cell line collections (Providers) Coriell; AG04446
Cell line databases/resources CLO; CLO_0034835
Encyclopedic resources Wikidata; Q54610236
Gene expression databases GEO; GSM6347
GEO; GSM6386
Entry history
Entry creation22-Sep-2015
Last entry update29-Jun-2023
Version number13