ID   AG04054
AC   CVCL_2A41
SY   AG 4054; AG04054A; AG04054B; GRC#0173
DR   CLO; CLO_0034761
DR   Coriell; AG04054
DR   GEO; GSM244109
DR   GEO; GSM244110
DR   GEO; GSM476002
DR   GEO; GSM3124568
DR   Wikidata; Q54609902
RX   CelloPub=CLPUB00597;
RX   PubMed=3745952;
RX   PubMed=6223188;
RX   PubMed=7176709;
RX   PubMed=7307581;
RX   PubMed=18631391;
RX   PubMed=19966276;
RX   PubMed=30567591;
CC   Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection.
CC   Population: Caucasian.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_2E07 ! AG11557
OI   CVCL_2G15 ! AG13442
SX   Male
AG   29Y
CA   Finite cell line
DT   Created: 22-09-15; Last updated: 29-06-23; Version: 13
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RX   CelloPub=CLPUB00597;
RG   National Institute on Aging;
RT   "1994 catalog of cell lines. NIA Aging Cell Repository.";
RL   (In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994).
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RX   PubMed=3745952; DOI=10.1111/1523-1747.ep12285424;
RA   Sephel G.C., Davidson J.M.;
RT   "Elastin production in human skin fibroblast cultures and its decline
RT   with age.";
RL   J. Invest. Dermatol. 86:279-285(1986).
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RX   PubMed=6223188; DOI=10.1016/0047-6374(83)90071-4;
RA   Chapman M.L., Zaun M.R., Gracy R.W.;
RT   "Changes in NAD levels in human lymphocytes and fibroblasts during
RT   aging and in premature aging syndromes.";
RL   Mech. Ageing Dev. 21:157-167(1983).
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RX   PubMed=7176709; DOI=10.1016/0047-6374(82)90061-6;
RA   Tollefsbol T.O., Zaun M.R., Gracy R.W.;
RT   "Increased lability of triosephosphate isomerase in progeria and
RT   Werner's syndrome fibroblasts.";
RL   Mech. Ageing Dev. 20:93-101(1982).
//
RX   PubMed=7307581; DOI=10.1159/000131624;
RA   Schneider E.L., Monticone R., Smith J., Braunschweiger K., Roberts T.;
RT   "Skin fibroblast cultures derived from members of the Baltimore
RT   longitudinal study: a new resource for studies of cellular aging.";
RL   Cytogenet. Cell Genet. 31:40-46(1981).
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RX   PubMed=18631391; DOI=10.1186/1742-4933-5-5;
RA   Kriete A., Mayo K.L., Yalamanchili N., Beggs W., Bender P., Kari C.,
RA   Rodeck U.;
RT   "Cell autonomous expression of inflammatory genes in biologically aged
RT   fibroblasts associated with elevated NF-kappaB activity.";
RL   Immun. Ageing 5:5.1-5.8(2008).
//
RX   PubMed=19966276; DOI=10.1093/nar/gkp1103;
RA   Johnson J.E., Cao K., Ryvkin P., Wang L.-S., Johnson F.B.;
RT   "Altered gene expression in the Werner and Bloom syndromes is
RT   associated with sequences having G-quadruplex forming potential.";
RL   Nucleic Acids Res. 38:1114-1122(2010).
//
RX   PubMed=30567591; DOI=10.1186/s13059-018-1599-6;
RA   Fleischer J.G., Schulte R., Tsai H.H., Tyagi S., Ibarra A.,
RA   Shokhirev M.N., Huang L., Hetzer M.W., Navlakha S.;
RT   "Predicting age from the transcriptome of human dermal fibroblasts.";
RL   Genome Biol. 19:221.1-221.8(2018).
//