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Cellosaurus HGADFN136 (CVCL_2A35)

[Text version]
Cell line name HGADFN136
Accession CVCL_2A35
Resource Identification Initiative To cite this cell line use: HGADFN136 (RRID:CVCL_2A35)
Comments Part of: Progeria Research Foundation cell lines.
Miscellaneous: Cell line no longer available.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Progeria (NCIt: C34951)
Hutchinson-Gilford progeria syndrome (ORDO: Orphanet_740)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Finite cell line
Publications

PubMed=16126733; DOI=10.1093/hmg/ddi326
Glynn M.W., Glover T.W.
Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.
Hum. Mol. Genet. 14:2959-2969(2005)

Cross-references
Encyclopedic resources Wikidata; Q54885945
Entry history
Entry creation22-Sep-2015
Last entry update29-Jun-2023
Version number9