ID   HCS-2
AC   CVCL_2918
SY   HCS2
DR   BioSample; SAMN03470913
DR   cancercelllines; CVCL_2918
DR   Cell_Model_Passport; SIDM01815
DR   DepMap; ACH-001515
DR   JCRB; JCRB1203
DR   JCRB; NIHS0405
DR   Wikidata; Q54881899
RX   PubMed=2979208;
RX   PubMed=9023415;
RX   PubMed=25877200;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Doubling time: ~65 hours (Note=At 17th passage) (PubMed=2979208); ~39 hours (Note=Lot 09092016) (JCRB=JCRB1203).
CC   HLA typing: A*24:02; B*52:01; C*12:02 (PubMed=9023415).
CC   Discontinued: JCRB; NIHS0405; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): DepMap=ACH-001515; JCRB=JCRB1203; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 11
ST   D16S539: 9,10
ST   D18S51: 13,14
ST   D19S433: 12,13
ST   D21S11: 31.2
ST   D2S1338: 24
ST   D3S1358: 16,18
ST   D5S818: 11,12
ST   D7S820: 10,12
ST   D8S1179: 13,14
ST   FGA: 23,24
ST   Penta D: 11,13
ST   Penta E: 5,21
ST   TH01: 6
ST   TPOX: 9,11
ST   vWA: 18
DI   NCIt; C180839; Cervical squamous cell carcinoma, not otherwise specified
DI   ORDO; Orphanet_213767; Squamous cell carcinoma of the cervix uteri
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   42Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 19
//
RX   PubMed=2979208;
RA   Morisawa T., Kuramoto H., Shimoda T., Sakamoto I., Kato Y., Hamano M.;
RT   "Establishment and characterization of a new SCC antigen producing
RT   cell line (HCS-2) from a carcinoma of the uterine cervix.";
RL   Hum. Cell 1:308-314(1988).
//
RX   PubMed=9023415; DOI=10.1006/cimm.1996.1062;
RA   Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.;
RT   "HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating
RT   lymphocytes of patients with non-small cell lung cancer.";
RL   Cell. Immunol. 175:101-110(1997).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//