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Cellosaurus Eos-HL-60 (CVCL_2892)

[Text version]
Cell line name Eos-HL-60
Accession CVCL_2892
Resource Identification Initiative To cite this cell line use: Eos-HL-60 (RRID:CVCL_2892)
Comments Population: Caucasian.
Omics: SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
STR profile Source(s): ECACC=96100920

Markers:
AmelogeninX
CSF1PO13,14
D5S81812
D7S82011,12
D13S3178,11
D16S53911
TH018
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ECACC; 96100920
Cell line databases/resources CLO; CLO_0002936
CLDB; cl5062
cancercelllines; CVCL_2892
LINCS_LDP; LCL-2055
Encyclopedic resources Wikidata; Q54832346
Gene expression databases GEO; GSM827454
Polymorphism and mutation databases Progenetix; CVCL_2892
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number27