ID   3A(tPA-30-1)
AC   CVCL_2820
SY   TPA30-1; TPA 30-1; tPA30-1
DR   CLO; CLO_0001325
DR   EFO; EFO_0022454
DR   ATCC; CRL-1583
DR   BioSample; SAMN03471399
DR   ECACC; 96020926
DR   Wikidata; Q54585261
RX   PubMed=206898;
RX   PubMed=3493529;
RX   PubMed=33043158;
CC   Characteristics: Expresses the transformed phenotype at the permissive temperature (33 Celsius) and the non-transformed phenotype at the restrictive temperature (40 Celsius).
CC   Senescence: Has a limited life expectancy of 15 to 18 passages before entering the crisis stage (ATCC=CRL-1583).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=ts30).
CC   Derived from site: In situ; Placenta; UBERON=UBERON_0001987.
ST   Source(s): ATCC=CRL-1583
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 11
ST   D16S539: 9,12
ST   D18S51: 12,20
ST   D19S433: 14,16.2
ST   D21S11: 28,29
ST   D2S1338: 20,22
ST   D3S1358: 14,15
ST   D5S818: 11,13
ST   D7S820: 10
ST   D8S1179: 13,14
ST   FGA: 21,25
ST   Penta D: 8,9
ST   Penta E: 7,14
ST   TH01: 9,9.3
ST   TPOX: 8,11
ST   vWA: 16,17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_H646 ! TPA30-6
OI   CVCL_H645 ! TPWT-2
SX   Female
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 17
//
RX   PubMed=206898; DOI=10.1073/pnas.75.3.1409; PMCID=PMC411481;
RA   Chou J.Y.;
RT   "Human placental cells transformed by tsA mutants of simian virus 40:
RT   a model system for the study of placental functions.";
RL   Proc. Natl. Acad. Sci. U.S.A. 75:1409-1413(1978).
//
RX   PubMed=3493529; DOI=10.1126/science.3493529;
RA   Wong G.G., Temple P.A., Leary A.C., Witek-Giannotti J.S., Yang Y.-C.,
RA   Brennan A., Chung M., Murtha P., Kriz R., Kaufman R.J., Ferenz C.R.,
RA   Sibley B.S., Turner K.J., Hewick R.M., Clark S.C., Yanai N., Yokota H.,
RA   Yamada M., Saito M., Motoyoshi K., Takaku F.;
RT   "Human CSF-1: molecular cloning and expression of 4-kb cDNA encoding
RT   the human urinary protein.";
RL   Science 235:1504-1508(1987).
//
RX   PubMed=33043158; DOI=10.1016/j.heliyon.2020.e04759; PMCID=PMC7536373;
RA   Ono A., Benny P., Griffith M., Litton C., Lee M.-J.;
RT   "Appropriate citation of placenta cell lines 3A(tPA-30-1) and 3A-sub E
RT   [post crisis of 3A(tPA-30-1)] in medical literature.";
RL   Heliyon 6:e04759.1-e04759.9(2020).
//