ID   SKG-II
AC   CVCL_2794
SY   SKGII; SKG-2; SKG2
DR   BioSample; SAMN03470893
DR   BioSample; SAMN03472779
DR   Cell_Model_Passport; SIDM01854
DR   Cosmic; 877460
DR   Cosmic; 1152538
DR   DepMap; ACH-001652
DR   JCRB; IFO50309
DR   JCRB; JCRB0171
DR   Wikidata; Q54954727
RX   CelloPub=CLPUB00434;
RX   CelloPub=CLPUB00481;
RX   PubMed=2429643;
RX   PubMed=2448191;
RX   PubMed=3029293;
RX   PubMed=9023415;
RX   PubMed=9436037;
RX   PubMed=9573483;
RX   PubMed=10457904;
RX   PubMed=25877200;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Doubling time: 31 hours (PubMed=10457904).
CC   HLA typing: A*24:02 (PubMed=9023415).
CC   Sequence variation: Mutation; HGNC; 7773; NF2; Simple; p.Ser87Ter (c.260C>A); Zygosity=Unspecified (DepMap=ACH-001652).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Discontinued: JCRB; JCRB0171; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): DepMap=ACH-001652; JCRB=IFO50309; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 8
ST   D16S539: 11
ST   D18S51: 18
ST   D19S433: 14,16.2
ST   D21S11: 28
ST   D2S1338: 20
ST   D3S1358: 15
ST   D5S818: 12
ST   D7S820: 11
ST   D8S1179: 13
ST   FGA: 22
ST   Penta D: 10
ST   Penta E: 12
ST   TH01: 7,9 (DepMap=ACH-001652; JCRB=IFO50309)
ST   TH01: 9 (PubMed=25877200)
ST   TPOX: 8,9
ST   vWA: 16,18
DI   NCIt; C27676; Human papillomavirus-related cervical squamous cell carcinoma
DI   ORDO; Orphanet_213767; Squamous cell carcinoma of the cervix uteri
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_VI91 ! SKG-IIB
SX   Female
AG   50Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 25
//
RX   CelloPub=CLPUB00434;
RA   Ishiwata I., Nozawa S., Kiguchi K., Kurihara S., Okumura H.;
RT   "Establishment of human uterine cervical cancer cell line and comparative
RT   studies between normal and malignant uterine cervical cells in vitro.";
RL   Nihon Sanka Fujinka Gakkai Zasshi 30:731-738(1978).
//
RX   CelloPub=CLPUB00481;
RA   Kuno H., Yoshida T.;
RT   "Detection of human papillomavirus types 16, 18, and 33 in cell lines
RT   derived from human genital organs by polymerase chain reaction.";
RL   Res. Commun. Inst. Ferment. Osaka 18:6-12(1997).
//
RX   PubMed=2429643; DOI=10.1111/j.1447-0756.1986.tb00192.x;
RA   Ishiwata I., Ishiwata C., Nozawa S., Ishikawa H.;
RT   "CA125 production by gynecologic tumors in vitro and its modulation
RT   induced by dibutyl cyclic adenosine monophosphate.";
RL   Asia Oceania J. Obstet. Gynaecol. 12:285-290(1986).
//
RX   PubMed=2448191; DOI=10.1016/0090-8258(88)90151-5;
RA   Ishiwata I., Ishiwata C., Soma M., Ono I., Nakaguchi T., Ishikawa H.;
RT   "Tumor angiogenic activity of gynecologic tumor cell lines on the
RT   chorioallantoic membrane.";
RL   Gynecol. Oncol. 29:87-93(1988).
//
RX   PubMed=3029293; DOI=10.1099/0022-1317-68-2-583;
RA   Shirasawa H., Tomita Y., Sekiya S., Takamizawa H., Simizu B.;
RT   "Integration and transcription of human papillomavirus type 16 and 18
RT   sequences in cell lines derived from cervical carcinomas.";
RL   J. Gen. Virol. 68:583-591(1987).
//
RX   PubMed=9023415; DOI=10.1006/cimm.1996.1062;
RA   Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.;
RT   "HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating
RT   lymphocytes of patients with non-small cell lung cancer.";
RL   Cell. Immunol. 175:101-110(1997).
//
RX   PubMed=9436037;
RA   Soma M., Ishiwata I., Ishiwata C., Nakaguchi T., Ono I., Kiguchi K.,
RA   Hashimoto H., Tachibana T., Ishikawa H., Nozawa S.;
RT   "Tissue reconstruction of gynecologic tumor cells in the rotation
RT   culture system.";
RL   Hum. Cell 10:175-181(1997).
//
RX   PubMed=9573483;
RA   Ishiwata I., Tokieda Y., Ishiwata C., Okane N., Iguchi M., Sato K.,
RA   Ishikawa H.;
RT   "Effects of feeder cells (human cancer cell lines) on the development
RT   of mouse embryos by co-culture.";
RL   Hum. Cell 10:237-246(1997).
//
RX   PubMed=10457904;
RA   Ishiwata I., Sudo T., Kiguchi K., Ishikawa H.;
RT   "Tumor angiogenesis factors produced by cancer cells.";
RL   Hum. Cell 12:37-46(1999).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//