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Cellosaurus TALL-104 (CVCL_2771)

[Text version]
Cell line name TALL-104
Accession CVCL_2771
Resource Identification Initiative To cite this cell line use: TALL-104 (RRID:CVCL_2771)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11386.
Characteristics: IL2 dependent.
Omics: Deep quantitative proteome analysis.
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: STR profile from personal communication of Leo I.R.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 8064; NUP214; Name(s)=NUP214-ABL1; Note=NUP214 exon 32 fused to ABL1 exon 2 (PubMed=15361874; PubMed=35354797).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y
Category Cancer cell line
STR profile Source(s): ATCC; Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10,11
D1S165616
D2S44111
D2S133820,25
D3S135815,18
D5S81812,13
D7S8207,13
D8S117911,14
D10S124813,14
D12S39122,23
D13S3179,12
D16S53912
D18S5112,13
D19S43314.2,15
D21S1130,31
D22S104511,16
DYS39110
FGA21,22
SE3316,19
TH017,9
TPOX8,9
vWA14,18

Run an STR similarity search on this cell line
Web pages http://www.galileoresearch.it/en/pipeline/TALL-104.html
Publications

PubMed=1706955; DOI=10.1182/blood.V77.7.1534.1534
O'Connor R., Cesano A., Lange B., Finan J., Nowell P.C., Clark S.C., Raimondi S.C., Rovera G., Santoli D.
Growth factor requirements of childhood acute T-lymphoblastic leukemia: correlation between presence of chromosomal abnormalities and ability to grow permanently in vitro.
Blood 77:1534-1545(1991)

PubMed=2039829; DOI=10.1182/blood.V77.11.2463.2463
Cesano A., O'Connor R., Lange B., Finan J., Rovera G., Santoli D.
Homing and progression patterns of childhood acute lymphoblastic leukemias in severe combined immunodeficiency mice.
Blood 77:2463-2474(1991)

Patent=US5272082
Santoli D., Rovera G., Cesano A.
Cytotoxic T-ALL cell lines and uses therefor.
Patent number US5272082, 21-Dec-1993

PubMed=11059767
Kruse C.A., Visonneau S., Kleinschmidt-DeMasters B.K., Gup C.J., Gomez G.G., Paul D.B., Santoli D.
The human leukemic T-cell line, TALL-104, is cytotoxic to human malignant brain tumors and traffics through brain tissue: implications for local adoptive immunotherapy.
Cancer Res. 60:5731-5739(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=15361874; DOI=10.1038/ng1425
Graux C., Cools J., Melotte C., Quentmeier H., Ferrando A.A., Levine R., Vermeesch J.R., Stul M., Dutta B., Boeckx N., Bosly A., Heimann P., Uyttebroeck A., Mentens N., Somers R., MacLeod R.A.F., Drexler H.G., Look A.T., Gilliland D.G., Michaux L., Vandenberghe P., Wlodarska I., Marynen P., Hagemeijer A.
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia.
Nat. Genet. 36:1084-1089(2004)

PubMed=17170727; DOI=10.1038/sj.leu.2404486
Sandberg Y., Verhaaf B., van Gastel-Mol E.J., Wolvers-Tettero I.L.M., de Vos J., MacLeod R.A.F., Noordzij J.G., Dik W.A., van Dongen J.J.M., Langerak A.W.
Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes.
Leukemia 21:230-237(2007)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5
Leo I.R., Aswad L., Stahl M., Kunold E., Post F., Erkers T., Struyf N., Mermelekas G., Joshi R.N., Gracia-Villacampa E., Ostling P., Kallioniemi O.-P., Pokrovskaja Tamm K., Siavelis I., Lehtio J., Vesterlund M., Jafari R.
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references
Cell line collections (Providers) AddexBio; C0003027/NA - Discontinued
ATCC; CRL-11386
Cell line databases/resources CLO; CLO_0009267
Anatomy/cell type resources BTO; BTO:0003740
Biological sample resources BioSample; SAMN03471335
Encyclopedic resources Wikidata; Q54971691
Gene expression databases GEO; GSM5137746
Polymorphism and mutation databases Cosmic; 683541
Cosmic; 2602910
Proteomic databases PRIDE; PXD023662
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number24