ID   UM-UC-4
AC   CVCL_2749
SY   UMUC4; University of Michigan-Urothelial Carcinoma-4
DR   BioGRID_ORCS_Cell_line; 1827
DR   Cell_Model_Passport; SIDM01910
DR   Cosmic; 1938701
DR   DepMap; ACH-001410
DR   ECACC; 08090501
DR   GEO; GSM1574566
DR   GEO; GSM1574569
DR   Wikidata; Q54990991
RX   PubMed=3761468;
RX   PubMed=25997541;
RX   PubMed=29732388;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: UBC-40 urothelial bladder cancer cell line index.
CC   Doubling time: 32 hours (PubMed=3761468).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Leu130Arg (c.389T>G); Zygosity=Unspecified (DepMap=ACH-001410).
CC   Omics: CNV analysis.
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
ST   Source(s): DepMap=ACH-001410; ECACC=08090501
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 9
ST   D16S539: 13
ST   D18S51: 16
ST   D21S11: 29
ST   D3S1358: 15,16
ST   D5S818: 11
ST   D7S820: 9,13
ST   D8S1179: 14
ST   FGA: 24
ST   Penta D: 12
ST   Penta E: 12,13
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 17,19
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 22
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RX   PubMed=3761468; DOI=10.1016/S0022-5347(17)45139-1;
RA   Grossman H.B., Wedemeyer G., Ren L.-Q., Wilson G.N., Cox B.;
RT   "Improved growth of human urothelial carcinoma cell cultures.";
RL   J. Urol. 136:953-959(1986).
//
RX   PubMed=25997541; DOI=10.1186/s12864-015-1450-3;
RA   Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B.,
RA   Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G.,
RA   Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D.,
RA   Chanock S.J., Valencia A., Real F.X.;
RT   "The UBC-40 Urothelial Bladder Cancer cell line index: a genomic
RT   resource for functional studies.";
RL   BMC Genomics 16:403.1-403.16(2015).
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RX   PubMed=29732388; DOI=10.3233/BLC-180167;
RA   Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.;
RT   "Systematic review: characteristics and preclinical uses of bladder
RT   cancer cell lines.";
RL   Bladder Cancer 4:169-183(2018).
//