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Cellosaurus UM-UC-11 (CVCL_2745)

[Text version]
Cell line name UM-UC-11
Synonyms UM-UC11; UMUC11; UC-11; University of Michigan-Urothelial Carcinoma-11
Accession CVCL_2745
Resource Identification Initiative To cite this cell line use: UM-UC-11 (RRID:CVCL_2745)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: UBC-40 urothelial bladder cancer cell line index.
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap; ECACC

Markers:
AmelogeninX,Y
CSF1PO10
D3S135815,16
D5S81812
D7S8208,12
D8S117911,13
D13S31711,14
D16S53911
D18S5113
D21S1130
FGA20,23
Penta D11,13
Penta E7,10
TH016,9
TPOX9
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=16469639; DOI=10.1016/S0022-5347(05)00323-X
Sabichi A.L., Keyhani A., Tanaka N., Delacerda J., Lee I.-L., Zou C.-P., Zhou J.-H., Benedict W.F., Grossman H.B.
Characterization of a panel of cell lines derived from urothelial neoplasms: genetic alterations, growth in vivo and the relationship of adenoviral mediated gene transfer to coxsackie adenovirus receptor expression.
J. Urol. 175:1133-1137(2006)

PubMed=18812553; DOI=10.1093/jnci/djn304
Park H.-S., Park W.S., Bondaruk J., Tanaka N., Katayama H., Lee S., Spiess P.E., Steinberg J.R., Wang Z., Katz R.L., Dinney C.P.N., Elias K.J., Lotan Y., Naeem R.C., Baggerly K., Sen S., Grossman H.B., Czerniak B.
Quantitation of Aurora kinase A gene copy number in urine sediments and bladder cancer detection.
J. Natl. Cancer Inst. 100:1401-1411(2008)

PubMed=19375735; DOI=10.1016/j.juro.2009.01.108
Chiong E., Dadbin A., Harris L.D., Sabichi A.L., Grossman H.B.
The use of short tandem repeat profiling to characterize human bladder cancer cell lines.
J. Urol. 181:2737-2748(2009)

PubMed=23401075; DOI=10.1002/path.4176
Guo Y.-N., Chekaluk Y., Zhang J.-M., Du J.-Y., Gray N.S., Wu C.-L., Kwiatkowski D.J.
TSC1 involvement in bladder cancer: diverse effects and therapeutic implications.
J. Pathol. 230:17-27(2013)

PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052
Allory Y., Beukers W., Sagrera A., Flandez M., Marques M., Marquez M., van der Keur K.A., Dyrskjot L., Lurkin I., Vermeij M., Carrato A., Lloreta J., Lorente J.A., Carrillo-de-Santa-Pau E., Masius R.G., Kogevinas M., Steyerberg E.W., van Tilborg A.A.G., Abas C., Orntoft T.F., Zuiverloon T.C.M., Malats N., Zwarthoff E.C., Real F.X.
Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome.
Eur. Urol. 65:360-366(2014)

PubMed=25997541; DOI=10.1186/s12864-015-1450-3
Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B., Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G., Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D., Chanock S.J., Valencia A., Real F.X.
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:403.1-403.16(2015)

PubMed=29732388; DOI=10.3233/BLC-180167
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) ECACC; 08090507
Cell line databases/resources Cell_Model_Passport; SIDM01407
DepMap; ACH-001413
Encyclopedic resources Wikidata; Q54990973
Gene expression databases GEO; GSM1567858
GEO; GSM1574591
Polymorphism and mutation databases Cosmic; 846279
Cosmic; 1927298
Cosmic; 1938706
Cosmic; 2037963
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number24