ID   TOU (TOU I-2)
AC   CVCL_2735
SY   TOU; TOU I-2
DR   CLO; CLO_0009383
DR   CLDB; cl4536
DR   ECACC; 93093001
DR   Wikidata; Q54972792
RX   PubMed=6438434;
WW   https://www.imgt.org/IMGTrepertoire/LocusGenes/locus/human/IGH/Hu_IGHcellines.html
CC   Population: Tunisian; Berber.
CC   Characteristics: Heterozygous for deletion of IGH G1-EP1-A1-GP-G2-G4 and of EP1-A1-GP.
CC   Sequence variation: Gene deletion; HGNC; HGNC:5478; IGHA1; Zygosity=Homozygous (PubMed=6438434).
CC   Sequence variation: Gene deletion; HGNC; HGNC:5523; IGHEP1; Zygosity=Homozygous (PubMed=6438434).
CC   Sequence variation: Gene deletion; HGNC; HGNC:5525; IGHG1; Zygosity=Heterozygous (PubMed=6438434).
CC   Sequence variation: Gene deletion; HGNC; HGNC:5526; IGHG2; Zygosity=Heterozygous (PubMed=6438434).
CC   Sequence variation: Gene deletion; HGNC; HGNC:5528; IGHG4; Zygosity=Heterozygous (PubMed=6438434).
CC   Sequence variation: Gene deletion; HGNC; HGNC:5529; IGHGP; Zygosity=Homozygous (PubMed=6438434).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=6438434;
RA   Lefranc M.-P., Lefranc G., de Lange G., Out T.A., van den Broek P.J.,
RA   van Nieuwkoop J., Radl J., Helal A.N., Chaabani H., van Loghem E.,
RA   Rabbitts T.H.;
RT   "Instability of the human immunoglobulin heavy chain constant region
RT   locus indicated by different inherited chromosomal deletions.";
RL   Mol. Biol. Med. 1:207-217(1983).
//