ID   TK6TGR
AC   CVCL_2733
SY   TK6 TGr.p1
DR   CLO; CLO_0009358
DR   CLDB; cl4520
DR   ECACC; 87020507
DR   Wikidata; Q54972537
RX   PubMed=22359172;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Sequence variation: Mutation; HGNC; 11272; SPTA1; Simple; p.Ser1163Ala (c.3487T>G); ClinVar=VCV000258929; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11830; TK1; Simple; p.Ala78Argfs*27 (c.231insC); Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Transformant: ChEBI; CHEBI:132982; Acridine half-mustard dihydrochloride (6-chloro-9-[3-(2-chloroethylamino)propylamino]-2-methoxyacridine dihydrochloride; Acridine mutagen ICR 191).
CC   Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
ST   Source(s): ECACC=87020507
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 11
ST   D16S539: 11,12
ST   D5S818: 12,13
ST   D7S820: 9,11
ST   TH01: 8,9.3
ST   TPOX: 8,11
ST   vWA: 17,20
DI   NCIt; C97074; Hereditary spherocytosis
DI   ORDO; Orphanet_822; Hereditary spherocytosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0561 ! TK6
SX   Male
AG   5Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 18
//
RX   PubMed=22359172; DOI=10.1007/BF00365082;
RA   Clark S.A., James S.E., Fitchett M.;
RT   "A new parental cell line for human x human hybridoma production.";
RL   Cytotechnology 1:359-363(1988).
//