Cellosaurus cell line TAK3 (CVCL

Cellosaurus TAK3 (CVCL_2729)

Cross-references
Cell line name	TAK3
Synonyms	TAK 3
Accession	CVCL_2729
Resource Identification Initiative	To cite this cell line use: TAK3 (RRID:CVCL_2729)
Comments	Population: Tunisian; Berber. Characteristics: Homozygous for deletion of IGH G1-EP1-A1-GP-G2-G4. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Gene deletion; HGNC; HGNC:5523; IGHEP1; Zygosity=Homozygous (PubMed=6438434; PubMed=6817143). Gene deletion; HGNC; HGNC:5525; IGHG1; Zygosity=Homozygous (PubMed=6438434; PubMed=6817143). Gene deletion; HGNC; HGNC:5526; IGHG2; Zygosity=Homozygous (PubMed=6438434; PubMed=6817143). Gene deletion; HGNC; HGNC:5528; IGHG4; Zygosity=Homozygous (PubMed=6438434; PubMed=6817143). Gene deletion; HGNC; HGNC:5529; IGHGP; Zygosity=Homozygous (PubMed=6438434; PubMed=6817143).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	75Y
Category	Transformed cell line
Web pages	https://www.imgt.org/IMGTrepertoire/LocusGenes/locus/human/IGH/Hu_IGHcellines.html
Publications	PubMed=6817143; DOI=10.1038/300760a0 Lefranc M.-P., Lefranc G., Rabbitts T.H. Inherited deletion of immunoglobulin heavy chain constant region genes in normal human individuals. Nature 300:760-762(1982) PubMed=6438434 Lefranc M.-P., Lefranc G., de Lange G., Out T.A., van den Broek P.J., van Nieuwkoop J., Radl J., Helal A.N., Chaabani H., van Loghem E., Rabbitts T.H. Instability of the human immunoglobulin heavy chain constant region locus indicated by different inherited chromosomal deletions. Mol. Biol. Med. 1:207-217(1983)
Cell line collections (Providers)	ECACC; 93093004
Cell line databases/resources	CLO; CLO_0009264 CLDB; cl4485
Encyclopedic resources	Wikidata; Q54971679
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	12