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Cellosaurus RT4/31 (CVCL_2715)

[Text version]
Cell line name RT4/31
Accession CVCL_2715
Resource Identification Initiative To cite this cell line use: RT4/31 (RRID:CVCL_2715)
Comments Population: Caucasian.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene fusion; HGNC; HGNC:3690; FGFR3 + HGNC; HGNC:11524; TACC3; Name(s)=FGFR3-TACC3 (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:12362; TSC1; Simple; p.Leu557Cysfs*72 (c.1669delC); ClinVar=VCV000048811; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0036 (RT-4)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) ECACC; 86082102
Cell line databases/resources cancercelllines; CVCL_2715
Encyclopedic resources Wikidata; Q54951364
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17