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Cellosaurus PE/CA-PJ41 (clone D2) (CVCL_2680)

[Text version]
Cell line name PE/CA-PJ41 (clone D2)
Synonyms PECAPJ41CLONED2; PE-CA-PJ41-cl D2; PE/CA-PJ-41; PE CA PJ41; PECAPJ41; Plaepi 41
Accession CVCL_2680
Resource Identification Initiative To cite this cell line use: PE/CA-PJ41 (clone D2) (RRID:CVCL_2680)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: KuDOS 95 cell line panel.
Population: Caucasian.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Misspelling: PECAPJ34CLONED2; GEO=GSM1374830.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; c.920-2A>T (IVS8-2A>T); Zygosity=Homozygous; Note=Splice acceptor mutation (DepMap=ACH-000732).
Genome ancestry Source: PubMed=30894373

Origin% genome
African2.91
Native American0
East Asian, North3.3
East Asian, South0
South Asian0
European, North62.2
European, South31.58
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): ECACC=98020207

Markers:
AmelogeninX
CSF1PO11,13
D5S81812
D7S8209,11
D13S31711,12
D16S53911,13
TH017
TPOX8
vWA15,19

Run an STR similarity search on this cell line
Publications

PubMed=9876219
Berndt A., Hyckel P., Konneker A., Katenkamp D., Kosmehl H.
Oral squamous cell carcinoma invasion is associated with a laminin-5 matrix re-organization but independent of basement membrane and hemidesmosome formation. Clues from an in vitro invasion model.
Invasion Metastasis 17:251-258(1997)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) ECACC; 98020207
Cell line databases/resources CLO; CLO_0008409
cancercelllines; CVCL_2680
Cell_Model_Passport; SIDM01323
DepMap; ACH-000732
Biological sample resources BioSample; SAMN10988012
Chemistry resources PharmacoDB; PE_CAPJ41_cloneD2_1258_2019
Encyclopedic resources Wikidata; Q54946884
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887510
GEO; GSM888592
GEO; GSM1374830
GEO; GSM1374831
Polymorphism and mutation databases Cosmic; 1339922
IARC_TP53; 28261
LiGeA; CCLE_664
Progenetix; CVCL_2680
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number27