ID   P4E6
AC   CVCL_2677
DR   BTO; BTO:0003540
DR   DepMap; ACH-001627
DR   ECACC; 10112301
DR   Wikidata; Q54937297
RX   PubMed=11121225;
RX   PubMed=17163777;
RX   PubMed=28094783;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Transfected with: UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
ST   Source(s): DepMap=ACH-001627; ECACC=10112301
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11
ST   D16S539: 11
ST   D18S51: 16,18
ST   D21S11: 27,30.2
ST   D3S1358: 16,17
ST   D5S818: 12
ST   D7S820: 7,8
ST   D8S1179: 10,14
ST   FGA: 25
ST   Penta D: 9,12
ST   Penta E: 11
ST   TH01: 7,9.3
ST   TPOX: 8
ST   vWA: 17,19
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 18
//
RX   PubMed=11121225; DOI=10.1667/0033-7587(2001)155[0133:IVMTSC]2.0.CO;2;
RA   Maitland N.J., Macintosh C.A., Hall J., Sharrard M., Quinn G.,
RA   Lang S.H.;
RT   "In vitro models to study cellular differentiation and function in
RT   human prostate cancers.";
RL   Radiat. Res. 155:133-142(2001).
//
RX   PubMed=17163777; DOI=10.1290/0511080.1;
RA   Lang S.H., Smith J., Hyde C., Macintosh C.A., Stower M.,
RA   Maitland N.J.;
RT   "Differentiation of prostate epithelial cell cultures by matrigel/
RT   stromal cell glandular reconstruction.";
RL   In Vitro Cell. Dev. Biol. Anim. 42:273-280(2006).
//
RX   PubMed=28094783; DOI=10.1038/srep40633;
RA   Harner-Foreman N., Vadakekolathu J., Laversin S.A., Mathieu M.G.,
RA   Reeder S., Pockley A.G., Rees R.C., Boocock D.J.;
RT   "A novel spontaneous model of epithelial-mesenchymal transition (EMT)
RT   using a primary prostate cancer derived cell line demonstrating
RT   distinct stem-like characteristics.";
RL   Sci. Rep. 7:40633-40633(2017).
//