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Cellosaurus MRC-9 (CVCL_2629)

[Text version]
Cell line name MRC-9
Synonyms MRC9; Medical Research Council cell strain-9
Accession CVCL_2629
Resource Identification Initiative To cite this cell line use: MRC-9 (RRID:CVCL_2629)
Comments Population: Caucasian.
Senescence: Can undergo at least 40 PDL (PubMed=113411). Senesces at 44 PDL (JCRB=IFO50072).
Virology: Susceptible to infection by a wide range of viruses (ECACC=85020202).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_3030 (MRC-9-30)CVCL_VF51 (USCBi001-A)
Sex of cell Female
Age at sampling 15FW
Category Finite cell line
STR profile Source(s): ATCC=CCL-212; ECACC=85020202; JCRB=IFO50072; JCRB=JCRB9060

Markers:
AmelogeninX
CSF1PO12
D2S133819,23
D3S135814,16
D5S81812,13
D7S82010,11
D8S117912,13
D13S3178,11
D16S53912
D18S5112,19
D19S43313.2,14
D21S1129,30.2
FGA22,24
Penta D12
Penta E5,12
TH016,8
TPOX11
vWA16,17

Run an STR similarity search on this cell line
Web pages Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=69
Publications

PubMed=1031681
Jacobs J.P.
Updated results on the karyology of the WI-38, MRC-5 and MRC-9 cell strains.
Dev. Biol. Stand. 37:155-156(1976)

PubMed=113411; DOI=10.1016/S0092-1157(79)80043-8
Jacobs J.P., Garrett A.J., Merton R.
Characteristics of a serially propagated human diploid cell designated MRC-9.
J. Biol. Stand. 7:113-122(1979)

PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222
Hay R.J., Williams C.D., Macy M.L., Lavappa K.S.
Cultured cell lines for research on pulmonary physiology available through the American Type Culture Collection.
Am. Rev. Respir. Dis. 125:222-232(1982)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ATCC; CCL-212
CLS; 300394
ECACC; 85020202
JCRB; IFO50072
JCRB; JCRB9060
KCLB; 10212 - Discontinued
Cell line databases/resources CLO; CLO_0007870
CLDB; cl3573
Biological sample resources BioSample; SAMN01821581
BioSample; SAMN01821703
BioSample; SAMN01821736
BioSample; SAMN03471472
Encyclopedic resources Wikidata; Q54906597
Gene expression databases GEO; GSM827585
GEO; GSM1887917
GEO; GSM1887962
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number22