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Cellosaurus Mero-25 (CVCL_2591)

[Text version]
Cell line name Mero-25
Synonyms MERO25
Accession CVCL_2591
Resource Identification Initiative To cite this cell line use: Mero-25 (RRID:CVCL_2591)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~48 hours (PubMed=2474517).
Transformant: ChEBI; CHEBI_46661; Asbestos.
Omics: Deep exome analysis.
Derived from site: In situ; Lung, pleura; UBERON=UBERON_0000977.
Disease Pleural biphasic mesothelioma (NCIt: C45665)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling >60Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001556; ECACC=09100102

Markers:
AmelogeninX,Y
CSF1PO11,12
D3S135815
D5S81811,12
D7S8209
D8S117913
D13S31712
D16S53911,12
D18S5118
D21S1130,31
FGA21
Penta D9,13
Penta E7,16
TH018
TPOX9
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=2474517; DOI=10.1002/ijc.2910440212
Versnel M.A., Bouts M.J., Hoogsteden H.C., van der Kwast T.H., Delahaye M., Hagemeijer A.
Establishment of human malignant mesothelioma cell lines.
Int. J. Cancer 44:256-260(1989)

PubMed=2790740; DOI=10.1016/0165-4608(89)90014-9
Versnel M.A., Hoogsteden H.C., Hagemeijer A., Bouts M.J., van der Kwast T.H., Delahaye M., Schaart G., Ramaekers F.C.S.
Characterization of three human malignant mesothelioma cell lines.
Cancer Genet. Cytogenet. 42:115-128(1989)

PubMed=25902174; DOI=10.1097/JTO.0000000000000493
Miyanaga A., Masuda M., Tsuta K., Kawasaki K., Nakamura Y., Sakuma T., Asamura H., Gemma A., Yamada T.
Hippo pathway gene mutations in malignant mesothelioma: revealed by RNA and targeted exon sequencing.
J. Thorac. Oncol. 10:844-851(2015)

PubMed=33567673; DOI=10.3390/cancers13040685; PMCID=PMC7915464
Keller M., Reis K., Hjerpe A., Dobra K., Aspenstrom P.
Cytoskeletal organization correlates to motility and invasiveness of malignant mesothelioma cells.
Cancers (Basel) 13:685.1-685.20(2021)

Cross-references
Cell line collections (Providers) ECACC; 09100102
Cell line databases/resources cancercelllines; CVCL_2591
Cell_Model_Passport; SIDM01788
DepMap; ACH-001556
Encyclopedic resources Wikidata; Q54905205
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21