Cellosaurus logo
expasy logo

Cellosaurus LMH (CVCL_2580)

[Text version]
Cell line name LMH
Synonyms Leghorn Male Hepatoma cell line
Accession CVCL_2580
Resource Identification Initiative To cite this cell line use: LMH (RRID:CVCL_2580)
Comments Group: Bird cell line.
Virology: Efficient cell line for duck hepatitis B virus (DHBV) DNA synthesis following transfection with viral constructs (PubMed=2352324).
Virology: Efficiently supports the replication of avian leukosis virus subgroup J (ALV-J) (PubMed=29720272).
Transformant: ChEBI; CHEBI:34873; N-nitrosodiethylamine (Diethylnitrosamine; DEN).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Epithelial cell; CL=CL_0000066.
Disease Chicken hepatoma (NCIt: C134558)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: White Leghorn L-M.
Hierarchy Children:
CVCL_A3FF (LMH serum-free suspension)CVCL_3465 (LMH/2A)
Sex of cell Male
Age at sampling 1Y4M
Category Cancer cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-71.html
Publications

PubMed=3607775
Kawaguchi T., Nomura K., Hirayama Y., Kitagawa T.
Establishment and characterization of a chicken hepatocellular carcinoma cell line, LMH.
Cancer Res. 47:4460-4464(1987)

PubMed=2330000; DOI=10.1210/mend-4-2-201
Binder R., MacDonald C.C., Burch J.B.E., Lazier C.B., Williams D.L.
Expression of endogenous and transfected apolipoprotein II and vitellogenin II genes in an estrogen responsive chicken liver cell line.
Mol. Endocrinol. 4:201-208(1990)

PubMed=2352324; DOI=10.1128/JVI.64.7.3249-3258.1990
Condreay L.D., Aldrich C.E., Coates L., Mason W.S., Wu T.-T.
Efficient duck hepatitis B virus production by an avian liver tumor cell line.
J. Virol. 64:3249-3258(1990)

PubMed=10564780; DOI=10.1016/s0304-4165(99)00159-2
Kolluri S., Elbirt K.K., Bonkovsky H.L.
Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison with primary chick embryo liver cells (CELC).
Biochim. Biophys. Acta 1472:658-667(1999)

PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022
Karger A., Bettin B., Lenk M., Mettenleiter T.C.
Rapid characterisation of cell cultures by matrix-assisted laser desorption/ionisation mass spectrometric typing.
J. Virol. Methods 164:116-121(2010)

PubMed=29720272; DOI=10.1186/s13567-018-0537-7
Li T.-F., Xie J., Lv L., Sun S., Dong X.-M., Xie Q., Liang G.-C., Xia C.-C., Shao H.-X., Qin A.-J., Ye J.-Q.
A chicken liver cell line efficiently supports the replication of ALV-J possibly through its high level viral receptor and efficient protein expression system.
Vet. Res. 49:41.1-41.5(2018)

PubMed=34737324; DOI=10.1038/s41598-021-00779-5
Lung O., Candlish R.C., Nebroski M., Kruckiewicz P., Buchanan C., Moniwa M.
High-throughput sequencing for species authentication and contamination detection of 63 cell lines.
Sci. Rep. 11:21657-21657(2021)

Cross-references
Cell line collections (Providers) ATCC; CRL-2117
BCRC; 60320
BCRJ; 0361
CCLV; CCLV-RIE 0417
CLS; 601411
JCRB; JCRB0237
NCBI_Iran; C592
Cell line databases/resources CLO; CLO_0007359
TOKU-E; 2215
Encyclopedic resources Wikidata; Q54902758
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number23