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Cellosaurus XP11BR LCL (CVCL_2556)

[Text version]
Cell line name XP11BR LCL
Synonyms Xeroderma Pigmentosum 11 BRighton LCL; LB205; 205
Accession CVCL_2556
Resource Identification Initiative To cite this cell line use: XP11BR LCL (RRID:CVCL_2556)
Comments Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:9181; POLH; Simple; p.Gly263Val (c.788G>T); dbSNP=rs1413703153; Zygosity=Homozygous (from autologous cell line XP11BR).
Disease Xeroderma pigmentosum variant type (NCIt: C141367)
Xeroderma pigmentosum variant (ORDO: Orphanet_90342)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_W049 ! XP11BR
Sex of cell Male
Age at sampling 62Y
Category Transformed cell line
Publications

PubMed=1372096; DOI=10.1016/0921-8777(92)90074-d
Arlett C.F., Harcourt S.A., Cole J., Green M.H.L., Anstey A.V.
A comparison of the response of unstimulated and stimulated T-lymphocytes and fibroblasts from normal, xeroderma pigmentosum and trichothiodystrophy donors to the lethal action of UV-C.
Mutat. Res. 273:127-135(1992)

Cross-references
Cell line collections (Providers) ECACC; 98062329
Encyclopedic resources Wikidata; Q54902045
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18