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Cellosaurus Karpas-384 (CVCL_2541)

[Text version]
Cell line name Karpas-384
Synonyms Karpas 384; KARPAS 384; KARPAS384
Accession CVCL_2541
Resource Identification Initiative To cite this cell line use: Karpas-384 (RRID:CVCL_2541)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~60 hours (ECACC=06120602).
Omics: Deep exome analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (DepMap=ACH-001097).
Disease Primary cutaneous T-cell non-Hodgkin lymphoma (NCIt: C3467)
Primary cutaneous T-cell lymphoma (ORDO: Orphanet_171901)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 48Y
Category Cancer cell line
Publications

PubMed=8391614
Dyer M.J.S., Nacheva E., Fischer P., Heward J.M., Labastide W.B., Karpas A.
A new human T-cell lymphoma cell line (Karpas 384) of the T-cell receptor gamma/delta lineage with translocation t(7:14) (p13;q11.2).
Leukemia 7:1047-1053(1993)

PubMed=7849311; DOI=10.1182/blood.V85.4.893.bloodjournal854893
Stranks G., Height S.E., Mitchell P., Jadayel D.M., Yuille M.A.R., De Lord C.F.M., Clutterbuck R.D., Treleaven J.G., Powles R.L., Nacheva E., Oscier D.G., Karpas A., Lenoir G.M., Smith S.D., Millar J.L., Catovsky D., Dyer M.J.S.
Deletions and rearrangement of CDKN2 in lymphoid malignancy.
Blood 85:893-901(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Cell line collections (Providers) ECACC; 06120602
Cell line databases/resources cancercelllines; CVCL_2541
Cell_Model_Passport; SIDM01737
DepMap; ACH-001097
Encyclopedic resources Wikidata; Q54899498
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20