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Cellosaurus HS-Sultan (CVCL_2516)

[Text version]
Cell line name HS-Sultan
Synonyms Hs-Sultan; HS-SULTAN; HS-sultan; HS Sultan; HSSultan; H. S. Sultan; SULTAN; Sultan
Accession CVCL_2516
Resource Identification Initiative To cite this cell line use: HS-Sultan (RRID:CVCL_2516)
Comments Problematic cell line: Contaminated. Shown to be a Jiyoye derivative (PubMed=10516762; PubMed=12592342; PubMed=20143388). Originally thought to originate from a plasma cell myeloma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00214.
Population: African; Nigerian.
Doubling time: 24 hours (PubMed=6365856).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Gln (c.394A>C); ClinVar=VCV000376628; Zygosity=Unspecified (from parent cell line).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*03:01,74:01
HLA-BB*53:01,58:01
HLA-CC*04:01,04:01
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1317 (Jiyoye)
Children:
CVCL_IU06 (LSM 2.7)
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-1484; ECACC=87012701; JCRB=JCRB9062

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133821
D3S135816,17
D5S81812
D7S8208,10
D8S117914,15
D13S31712
D16S53910,11
D18S5112,19
D19S43312,15
D21S1128,36
FGA23,24
Penta D2.2,12
Penta E8,12
TH017,9
TPOX6,8
vWA15,19

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=4549735; DOI=10.1038/250507a0
Harris N.S.
Plasma cell surface antigen on human blood lymphocytes.
Nature 250:507-509(1974)

PubMed=6365856; DOI=10.1016/0198-8859(84)90041-7
Schwaber J.F., Posner M.R., Schlossman S.F., Lazarus H.
Human-human hybrids secreting pneumococcal antibodies.
Hum. Immunol. 9:137-143(1984)

PubMed=10516762; DOI=10.1038/sj.leu.2401510
Drexler H.G., Dirks W.G., MacLeod R.A.F.
False human hematopoietic cell lines: cross-contaminations and misinterpretations.
Leukemia 13:1601-1607(1999)

DOI=10.1007/0-306-46877-8_4
Jernberg-Wiklund H., Nilsson K.
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M.J., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=19220422; DOI=10.1111/j.1600-0609.2009.01211.x
Kamihira S., Terada C., Sasaki D., Yanagihara K., Tsukasaki K., Hasegawa H., Yamada Y.
Aberrant p53 protein expression and function in a panel of hematopoietic cell lines with different p53 mutations.
Eur. J. Haematol. 82:301-307(2009)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=29892436; DOI=10.1098/rsos.172472; PMCID=PMC5990783
Shioda S., Kasai F., Watanabe K., Kawakami K., Ohtani A., Iemura M., Ozawa M., Arakawa A., Hirayama N., Kawaguchi E., Tano T., Miyata S., Satoh M., Shimizu N., Kohara A.
Screening for 15 pathogenic viruses in human cell lines registered at the JCRB Cell Bank: characterization of in vitro human cells by viral infection.
R. Soc. Open Sci. 5:172472-172472(2018)

Cross-references
Cell line collections (Providers) ATCC; CRL-1484
ECACC; 87012701
JCRB; JCRB9062
Cell line databases/resources CLO; CLO_0004264
CLDB; cl1723
cancercelllines; CVCL_2516
IGRhCellID; HSSultan
LINCS_LDP; LCL-2036
Anatomy/cell type resources BTO; BTO_0003035
Biological sample resources BioSample; SAMN03151805
Chemistry resources PharmacoDB; HSSultan_616_2019
Encyclopedic resources Wikidata; Q54896292
Experimental variables resources EFO; EFO_0002199
Gene expression databases ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-2706
Polymorphism and mutation databases Cosmic; 759913
Cosmic; 846385
IARC_TP53; 27008
Progenetix; CVCL_2516
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number34