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Cellosaurus HR5 (CVCL_2505)

[Text version]
Cell line name HR5
Synonyms HeLa rtTA HR5; HeLa HR5
Accession CVCL_2505
Resource Identification Initiative To cite this cell line use: HR5 (RRID:CVCL_2505)
Comments Population: African American.
Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Arg360del).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_2506 (HR5-CL11)CVCL_GZ13 (HRL9)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX
CSF1PO9,10,11
D2S133817
D3S135815,16,18
D5S81811,12
D7S8208,12
D8S117912
D13S31712,13.3
D16S5399,10,13
D18S5113,16
D19S43313,14,16
D21S1127,29
FGA18,21
Penta D8
Penta E7,17
TH017
TPOX12
vWA16,18

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Publications

PubMed=7792603; DOI=10.1126/science.7792603
Gossen M., Freundlieb S., Bender G., Muller G., Hillen W., Bujard H.
Transcriptional activation by tetracyclines in mammalian cells.
Science 268:1766-1769(1995)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

Cross-references
Cell line collections (Providers) ECACC; 95091409
Cell line databases/resources CLO; CLO_0003834
CLDB; cl1708
Biological sample resources BioSample; SAMN03470982
Encyclopedic resources Wikidata; Q54895210
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number20