Cellosaurus cell line H314 (CVCL

Cellosaurus H314 (CVCL_2460)

Cross-references
Cell line name	H314
Accession	CVCL_2460
Resource Identification Initiative	To cite this cell line use: H314 (RRID:CVCL_2460)
Comments	Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Phe (c.527G>T); ClinVar=VCV000376569; Zygosity=Homozygous (PubMed=7633286). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys373Glu (c.1117A>G); Zygosity=Homozygous (PubMed=7633286).
Disease	Floor of mouth squamous cell carcinoma (NCIt: C4041) Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	82Y
Category	Cancer cell line
Publications	PubMed=1692339; DOI=10.1002/path.1711600313 Prime S.S., Nixon S.V.R., Crane I.J., Stone A., Matthews J.B., Maitland N.J., Remnant L., Powell S.K., Game S.M., Scully C. The behaviour of human oral squamous cell carcinoma in cell culture. J. Pathol. 160:259-269(1990) PubMed=1744799; DOI=10.1002/path.1711650208 Mutlu S., Matthews J.B., Midda M., Scully C., Prime S.S. MHC antigen expression in human oral squamous carcinoma cell lines. J. Pathol. 165:129-136(1991) PubMed=7633286; DOI=10.1016/0964-1955(94)00030-8 Yeudall W.A., Paterson I.C., Patel V., Prime S.S. Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53. Eur. J. Cancer B. Oral Oncol. 31:136-143(1995)
Cell line collections (Providers)	CancerTools; 153421 ECACC; 06092003 - Discontinued Ximbio; 153421
Cell line databases/resources	cancercelllines; CVCL_2460
Encyclopedic resources	Wikidata; Q54872065
Polymorphism and mutation databases	Cosmic; 716675 Cosmic; 916369 Cosmic; 928236
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	18