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Cellosaurus h1RPE7 (CVCL_2459)

[Text version]
Cell line name h1RPE7
Synonyms h1RPE-7
Accession CVCL_2459
Resource Identification Initiative To cite this cell line use: h1RPE7 (RRID:CVCL_2459)
Comments Doubling time: ~24 hours (ECACC=09061602).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9W31 ! h1RPE116
Sex of cell Female
Age at sampling 50Y
Category Transformed cell line
STR profile Source(s): ECACC=09061602

Markers:
AmelogeninX
CSF1PO10,13
D5S8189,13
D7S8209,10
D13S31712
D16S53912
TH017,9.3
TPOX8
vWA16,19

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Publications

PubMed=11504951; DOI=10.1073/pnas.171266298; PMCID=PMC55557
Lund R.D., Adamson P., Sauve Y., Keegan D.J., Girman S.V., Wang S.-M., Winton H.L., Kanuga N., Kwan A.S.L., Beauchene L., Zerbib A., Hetherington L., Couraud P.-O., Coffey P., Greenwood J.
Subretinal transplantation of genetically modified human cell lines attenuates loss of visual function in dystrophic rats.
Proc. Natl. Acad. Sci. U.S.A. 98:9942-9947(2001)

PubMed=11818403
Kanuga N., Winton H.L., Beauchene L., Koman A., Zerbib A., Halford S., Couraud P.-O., Keegan D.J., Coffey P., Lund R.D., Adamson P., Greenwood J.
Characterization of genetically modified human retinal pigment epithelial cells developed for in vitro and transplantation studies.
Invest. Ophthalmol. Vis. Sci. 43:546-555(2002)

PubMed=25177495; DOI=10.1155/2014/801787; PMCID=PMC4142280
Kuznetsova A.V., Kurinov A.M., Aleksandrova M.A.
Cell models to study regulation of cell transformation in pathologies of retinal pigment epithelium.
J. Ophthalmol. 2014:801787.1-801787.18(2014)

Cross-references
Cell line collections (Providers) ECACC; 09061602
Encyclopedic resources Wikidata; Q54871994
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16