ID   DMS 92
AC   CVCL_2439
SY   DMS-92; DMS92; Darmouth Medical School 92
DR   CLO; CLO_0002801
DR   CLDB; cl1083
DR   BioSample; SAMN03472958
DR   cancercelllines; CVCL_2439
DR   Cosmic; 929980
DR   Cosmic; 2648006
DR   Cosmic; 2668271
DR   ECACC; 95062825
DR   GEO; GSM827447
DR   IARC_TP53; 120
DR   Progenetix; CVCL_2439
DR   Wikidata; Q54831313
RX   PubMed=1855224;
RX   PubMed=2986244;
RX   PubMed=6266631;
RX   PubMed=9212023;
RX   PubMed=9744504;
RX   PubMed=20215515;
RX   PubMed=25877200;
CC   Doubling time: 5.5 days (PubMed=6266631; PubMed=2986244).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>A); ClinVar=VCV000142714; Zygosity=Unspecified (PubMed=1855224).
CC   Omics: SNP array analysis.
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): ECACC=95062825; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 11,13
ST   D13S317: 12
ST   D16S539: 12,13
ST   D18S51: 13,14
ST   D21S11: 28,31
ST   D3S1358: 15
ST   D5S818: 11,13
ST   D7S820: 10,11
ST   D8S1179: 10,12
ST   FGA: 22,24
ST   Penta D: 11,12
ST   Penta E: 10,12
ST   TH01: 9.3
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   39Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 22
//
RX   PubMed=1855224;
RA   Lehman T.A., Bennett W.P., Metcalf R.A., Welsh J.A., Ecker J.,
RA   Modali R.V., Ullrich S., Romano J.W., Appella E., Testa J.R.,
RA   Gerwin B.I., Harris C.C.;
RT   "p53 mutations, ras mutations, and p53-heat shock 70 protein complexes
RT   in human lung carcinoma cell lines.";
RL   Cancer Res. 51:4090-4096(1991).
//
RX   PubMed=2986244; DOI=10.1007/978-3-642-82372-5_5;
RA   Vindelov L.L., Hansen H.H., Spang-Thomsen M.;
RT   "Growth characteristics and heterogeneity of small cell carcinoma of
RT   the lung.";
RL   Recent Results Cancer Res. 97:47-54(1985).
//
RX   PubMed=6266631; DOI=10.1002/1097-0142(19800301)45:5<906::AID-CNCR2820450513>3.0.CO;2-H;
RA   Pettengill O.S., Sorenson G.D., Wurster-Hill D.H., Curphey T.J.,
RA   Noll W.W., Cate C.C., Maurer L.H.;
RT   "Isolation and growth characteristics of continuous cell lines from
RT   small-cell carcinoma of the lung.";
RL   Cancer 45:906-918(1980).
//
RX   PubMed=9212023; DOI=10.1016/S0360-3016(97)00245-9;
RA   Krarup M., Poulsen H.S., Spang-Thomsen M.;
RT   "Cellular radiosensitivity of small-cell lung cancer cell lines.";
RL   Int. J. Radiat. Oncol. Biol. Phys. 38:191-196(1997).
//
RX   PubMed=9744504; DOI=10.1038/bjc.1998.553; PMCID=PMC2063065;
RA   Damstrup L., Voldborg B.G.R., Spang-Thomsen M., Brunner N.,
RA   Poulsen H.S.;
RT   "In vitro invasion of small-cell lung cancer cell lines correlates
RT   with expression of epidermal growth factor receptor.";
RL   Br. J. Cancer 78:631-640(1998).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//