Cellosaurus logo
expasy logo

Cellosaurus UPCI-SCC-172 (CVCL_2231)

[Text version]
Cell line name UPCI-SCC-172
Synonyms UPCI:SCC172; SCC172
Accession CVCL_2231
Resource Identification Initiative To cite this cell line use: UPCI-SCC-172 (RRID:CVCL_2231)
Comments Population: Caucasian.
Doubling time: ~50 hours (DSMZ=ACC-661).
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr155Pro (c.463A>C); Zygosity=Unspecified (PubMed=12872257).
Disease Oropharyngeal squamous cell carcinoma (NCIt: C8181)
Squamous cell carcinoma of the oropharynx (ORDO: Orphanet_500478)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-661

Markers:
AmelogeninX
CSF1PO11
D2S133817,25
D3S135816,17
D5S81812
D7S8209,11
D8S117913
D13S31711
D16S53910
D18S5111
D19S43313,15
D21S1129,33.2
FGA22,24
Penta D13
Penta E11,13
TH019.3
TPOX11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=12872257; DOI=10.1002/humu.10248
Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M., Ishwad C.S., Jarvik J.W.
Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping.
Hum. Mutat. 22:158-165(2003)

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692
White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L., Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T., Gollin S.M.
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=24142626; DOI=10.1002/gcc.22115; PMCID=PMC5520977
Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W., Vlad A., Gollin S.M.
Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.
Genes Chromosomes Cancer 53:25-37(2014)

Cross-references
Cell line collections (Providers) DSMZ; ACC-661
Cell line databases/resources DSMZCellDive; ACC-661
Biological sample resources BioSample; SAMN03473475
Encyclopedic resources Wikidata; Q54991688
Polymorphism and mutation databases IARC_TP53; 18367
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17