ID   UPCI-SCC-111
AC   CVCL_2226
SY   UPCI:SCC111; SCC111; SCC-111
DR   BioSample; SAMN03473480
DR   cancercelllines; CVCL_2226
DR   Cosmic; 927220
DR   Cosmic; 932154
DR   DepMap; ACH-001696
DR   DSMZ; ACC-666
DR   DSMZCellDive; ACC-666
DR   IARC_TP53; 18361
DR   Wikidata; Q54991668
RX   PubMed=12872257;
RX   PubMed=17112776;
RX   PubMed=17681875;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Caucasian.
CC   Doubling time: ~40 hours (DSMZ=ACC-666).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Unspecified (PubMed=12872257).
CC   Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
ST   Source(s): DSMZ=ACC-666
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,13
ST   D16S539: 9,12
ST   D18S51: 16.2
ST   D19S433: 14
ST   D21S11: 29,30,31
ST   D2S1338: 19,26
ST   D3S1358: 17
ST   D5S818: 12
ST   D7S820: 8,10
ST   D8S1179: 13,14
ST   FGA: 20
ST   Penta D: 11,14
ST   Penta E: 13
ST   TH01: 8,10
ST   TPOX: 8,11
ST   vWA: 18
DI   NCIt; C4041; Floor of mouth squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 22
//
RX   PubMed=12872257; DOI=10.1002/humu.10248;
RA   Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M.,
RA   Ishwad C.S., Jarvik J.W.;
RT   "Detection and assignment of TP53 mutations in tumor DNA using peptide
RT   mass signature genotyping.";
RL   Hum. Mutat. 22:158-165(2003).
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003;
RA   Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W.,
RA   Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.;
RT   "Chromosomal imbalances in oral squamous cell carcinoma: examination
RT   of 31 cell lines and review of the literature.";
RL   Oral Oncol. 44:369-382(2008).
//