ID   UPCI-SCC-072
AC   CVCL_2223
SY   UPCI:SCC072; SCC072
DR   BioSample; SAMN03473421
DR   cancercelllines; CVCL_2223
DR   DepMap; ACH-001693
DR   DSMZ; ACC-667
DR   DSMZCellDive; ACC-667
DR   IARC_TP53; 18355
DR   Wikidata; Q54991601
RX   PubMed=12872257;
RX   PubMed=17112776;
RX   PubMed=17681875;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Caucasian.
CC   Doubling time: ~120 hours (DSMZ=ACC-667).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His179Asn (c.535C>A); ClinVar=VCV000376609; Zygosity=Unspecified (PubMed=12872257).
CC   Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372.
ST   Source(s): DSMZ=ACC-667
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 11,12
ST   D18S51: 12,16
ST   D19S433: 13
ST   D21S11: 17,24
ST   D2S1338: 17,24
ST   D3S1358: 17
ST   D5S818: 14
ST   D7S820: 11,12
ST   D8S1179: 13,15
ST   FGA: 21,23
ST   Penta D: 13
ST   Penta E: 5,7
ST   TH01: 6
ST   TPOX: 8
ST   vWA: 15
DI   NCIt; C8183; Tonsillar squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   61Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 22
//
RX   PubMed=12872257; DOI=10.1002/humu.10248;
RA   Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M.,
RA   Ishwad C.S., Jarvik J.W.;
RT   "Detection and assignment of TP53 mutations in tumor DNA using peptide
RT   mass signature genotyping.";
RL   Hum. Mutat. 22:158-165(2003).
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003;
RA   Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W.,
RA   Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.;
RT   "Chromosomal imbalances in oral squamous cell carcinoma: examination
RT   of 31 cell lines and review of the literature.";
RL   Oral Oncol. 44:369-382(2008).
//