ID   UPCI-SCC-040
AC   CVCL_2222
SY   UPCI:SCC040; UPCISCC040; SCC040
DR   BioSample; SAMN03473474
DR   ChEMBL-Cells; CHEMBL4482982
DR   ChEMBL-Targets; CHEMBL4483277
DR   DepMap; ACH-001692
DR   DSMZ; ACC-660
DR   DSMZCellDive; ACC-660
DR   PubChem_Cell_line; CVCL_2222
DR   Wikidata; Q54991575
RX   PubMed=17112776;
RX   PubMed=17681875;
RX   PubMed=24142626;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Caucasian.
CC   Doubling time: ~70-80 hours (DSMZ=ACC-660).
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
ST   Source(s): DepMap=ACH-001692; DSMZ=ACC-660
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 8,12
ST   D16S539: 11
ST   D18S51: 10
ST   D19S433: 13
ST   D21S11: 30
ST   D2S1338: 17,20
ST   D3S1358: 17
ST   D5S818: 10,11
ST   D7S820: 9,10
ST   D8S1179: 14 (DSMZ=ACC-660)
ST   D8S1179: 14,16 (DepMap=ACH-001692)
ST   FGA: 20,21
ST   Penta D: 9
ST   Penta E: 12
ST   TH01: 6,8
ST   TPOX: 11
ST   vWA: 17 (DSMZ=ACC-660)
ST   vWA: 17,18 (DepMap=ACH-001692)
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   50Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 19
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003;
RA   Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W.,
RA   Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.;
RT   "Chromosomal imbalances in oral squamous cell carcinoma: examination
RT   of 31 cell lines and review of the literature.";
RL   Oral Oncol. 44:369-382(2008).
//
RX   PubMed=24142626; DOI=10.1002/gcc.22115;
RA   Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W.,
RA   Vlad A., Gollin S.M.;
RT   "Upregulation of the ATR-CHEK1 pathway in oral squamous cell
RT   carcinomas.";
RL   Genes Chromosomes Cancer 53:25-37(2014).
//