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Cellosaurus SPI-802 (CVCL_2201)

[Text version]
Cell line name SPI-802
Accession CVCL_2201
Resource Identification Initiative To cite this cell line use: SPI-802 (RRID:CVCL_2201)
Comments Problematic cell line: Contaminated. Shown to be a K-562 derivative (PubMed=10508494; PubMed=12592342; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00161.
Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-92

Markers:
AmelogeninX
CSF1PO10
D2S133817
D3S135816
D5S81812
D7S8209,11
D8S117912
D13S3178
D16S53911,12
D18S5115,16
D19S43314,15
D21S1129,30
FGA21,22
Penta D9,13
Penta E5,14
TH019.3
TPOX8,9
vWA16

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=6958338; DOI=10.1182/blood.V60.6.1429.1429
Komiyama A., Kawai H., Miyagawa Y., Akabane T.
Childhood lymphoblastic leukemia with natural killer activity: establishment of the leukemia cell lines retaining the activity.
Blood 60:1429-1436(1982)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) DSMZ; ACC-92 - Discontinued
Cell line databases/resources CLO; CLO_0009123
CLDB; cl4394
DSMZCellDive; ACC-92
Biological sample resources BioSample; SAMN03151815
Encyclopedic resources Wikidata; Q54955573
Polymorphism and mutation databases Cosmic; 787508
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number29