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Cellosaurus MOLM-20 (CVCL_2121)

[Text version]
Cell line name MOLM-20
Synonyms MOLM20
Accession CVCL_2121
Resource Identification Initiative To cite this cell line use: MOLM-20 (RRID:CVCL_2121)
Comments Part of: LL-100 blood cancer cell line panel.
Population: Japanese.
Doubling time: ~70 hours (DSMZ=ACC-591).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:7132; KMT2A + HGNC; HGNC:25589; SEPTIN11; Name(s)=KMT2A-SEPTIN11, KMT2A-SEPT11, MLL-SEPT11 (PubMed=31160637; DSMZ=ACC-591).
HLA typing Source: DSMZCellDive=ACC-591
Class I
HLA-AA*26:02:01,26:03:01
HLA-BB*15:01:01,40:06:01
HLA-CC*03:03:01,08:01:01
Class II
HLA-DPDPA1*01:03:01,01:03:01
DPB1*02:01:02,02:01:02
HLA-DRDRA*01:01:01,01:01:01
DRB1*09:01:02,09:01:02
Disease Chronic neutrophilic leukemia (NCIt: C3179)
Chronic neutrophilic leukemia (ORDO: Orphanet_86829)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_V650 ! CNLBC1
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-591

Markers:
AmelogeninX
CSF1PO11,12
D2S133817,19
D3S135815
D5S81811
D7S82010,11
D8S117910
D13S3178,11
D16S53913
D18S5114,15
D19S43312,14
D21S1129,30
FGA21,22
Penta D10,12
Penta E8,12
TH016
TPOX9,11
vWA17

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Publications

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K.G., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-591
Cell line databases/resources DSMZCellDive; ACC-591
Biological sample resources BioSample; SAMN03473490
Encyclopedic resources Wikidata; Q54906328
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
Polymorphism and mutation databases Cosmic; 1012098
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number24