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Cellosaurus LCL 721 (CVCL_2102)

[Text version]
Cell line name LCL 721
Synonyms LCL-721; 721; 721 LCL; B-LCL 721; LCL721
Accession CVCL_2102
Resource Identification Initiative To cite this cell line use: LCL 721 (RRID:CVCL_2102)
Comments Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
HLA typing Source: IPD-IMGT/HLA=10972
Class I
HLA-AA*01:01:01:01,02:01:01:01
HLA-BB*08:01:01,51:01:01
HLA-CC*07:01:01,01:02:01
Class II
HLA-DPDPA1*01:03,02:01:02
DPB1*02:01:02,04:01
HLA-DQDQB1*05:01:01
HLA-DRDRB1*01:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D326 (LCL 721.114)CVCL_D329 (LCL 721.127)CVCL_D328 (LCL 721.144)
CVCL_6260 (LCL 721.174)CVCL_6261 (LCL 721.180)CVCL_D327 (LCL 721.184)
CVCL_6262 (LCL 721.22)CVCL_D325 (LCL 721.220)CVCL_E420 (LCL 721.45)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=6933474; DOI=10.1073/pnas.77.7.4251; PMCID=PMC349810
Kavathas P.B., Bach F.H., DeMars R.I.
Gamma ray-induced loss of expression of HLA and glyoxalase I alleles in lymphoblastoid cells.
Proc. Natl. Acad. Sci. U.S.A. 77:4251-4255(1980)

PubMed=30844424; DOI=10.1016/j.humimm.2019.03.001; PMCID=PMC6599558
Creary L.E., Guerra S.G., Chong W., Brown C.J., Turner T.R., Robinson J., Bultitude W.P., Mayor N.P., Marsh S.G.E., Saito K., Lam K., Duke J.L., Mosbruger T.L., Ferriola D., Monos D.S., Willis A., Askar M., Fischer G.F., Saw C.L., Ragoussis J., Petrek M., Serra-Pages C., Juan Otero M., Stavropoulos-Giokas C., Dinou A., Ameen R., Al Shemmari S., Spierings E., Gendzekhadze K., Morris G.P., Zhang Q.-H., Kashi Z., Hsu S., Gangavarapu S., Mallempati K.C., Yamamoto F., Osoegawa K., Vayntrub T., Chang C.-J., Hansen J.A., Fernandez-Vina M.A.
Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: report from the 17th International HLA and Immunogenetics Workshop.
Hum. Immunol. 80:449-460(2019)

Cross-references
Cell line collections (Providers) ECACC; 09071301
Cell line databases/resources dbMHC; 48948
IHW; IHW09249
IPD-IMGT/HLA; 10972
Anatomy/cell type resources BTO; BTO_0006531
Encyclopedic resources Wikidata; Q54902205
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18