ID   L-5178-Y
AC   CVCL_2097
SY   L5178Y; LY
DR   BTO; BTO_0000795
DR   CLO; CLO_0007195
DR   CLO; CLO_0050168
DR   CLDB; cl3133
DR   ArrayExpress; E-TOXM-1
DR   ArrayExpress; E-TOXM-2
DR   ArrayExpress; E-TOXM-3
DR   ArrayExpress; E-TOXM-4
DR   ArrayExpress; E-TOXM-5
DR   ArrayExpress; E-TOXM-6
DR   ArrayExpress; E-TOXM-7
DR   ArrayExpress; E-TOXM-8
DR   ArrayExpress; E-TOXM-9
DR   ChEMBL-Cells; CHEMBL3307690
DR   ChEMBL-Targets; CHEMBL614720
DR   DSMZ; ACC-320
DR   DSMZCellDive; ACC-320
DR   ECACC; 87111908
DR   JCRB; JCRB0709
DR   Lonza; 1262
DR   PubChem_Cell_line; CVCL_2097
DR   RCB; RCB0135
DR   Wikidata; Q54900871
RX   PubMed=221956;
RX   PubMed=4321087;
RX   PubMed=6173370;
RX   PubMed=6413855;
RX   PubMed=6724617;
RX   PubMed=7565900;
RX   PubMed=15033590;
CC   Doubling time: 14.1 +- 1.6 hours (PubMed=221956); 11.3 hours (PubMed=6173370); ~20 hours (DSMZ=ACC-320); 10 hours (Note=Lot 07032005) (JCRB=JCRB0709).
CC   Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
CC   Cell type: T-cell; CL=CL_0000084.
CC   Breed/subspecies: DBA/2.
DI   NCIt; C134997; Mouse thymic lymphoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
AG   8M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 19
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RX   PubMed=221956; DOI=10.2307/3575014;
RA   Sato K., Hieda N.;
RT   "Isolation and characterization of a mutant mouse lymphoma cell
RT   sensitive to methyl methanesulfonate and X rays.";
RL   Radiat. Res. 78:167-171(1979).
//
RX   PubMed=4321087;
RA   Kessel D.H., Bosmann H.B.;
RT   "On the characteristics of actinomycin D resistance in L5178Y cells.";
RL   Cancer Res. 30:2695-2701(1970).
//
RX   PubMed=6173370; DOI=10.7164/antibiotics.34.1210;
RA   Suzuki H., Nishimura T., Tanaka N.;
RT   "Drug sensitivity and some characteristics of a bleomycin-resistant
RT   subline of mouse lymphoblastoma L5178Y cells.";
RL   J. Antibiot. 34:1210-1212(1981).
//
RX   PubMed=6413855; DOI=10.1016/0165-7992(83)90215-4;
RA   Sato K., Hieda-Shiomi N., Hama-Inaba H.;
RT   "X-ray-sensitive mutant mouse cells with various sensitivities to
RT   chemical mutagens.";
RL   Mutat. Res. 121:281-285(1983).
//
RX   PubMed=6724617; DOI=10.1007/BF02619582;
RA   Ankel E.G., Zirneski J., Ring B.J., Holcenberg J.S.;
RT   "Effect of asparaginase on cell membranes of sensitive and resistant
RT   mouse lymphoma cells.";
RL   In Vitro 20:376-384(1984).
//
RX   PubMed=7565900; DOI=10.1016/0165-7992(95)00027-5;
RA   Zhang L.-S., Honma M., Hayashi M., Suzuki T., Matsuoka A., Sofuni T.;
RT   "A comparative study of TK6 human lymphoblastoid and L5178Y mouse
RT   lymphoma cell lines in the in vitro micronucleus test.";
RL   Mutat. Res. 347:105-115(1995).
//
RX   PubMed=15033590; DOI=10.1289/ehp.6709; PMCID=PMC1241894;
RA   Newton R.K., Aardema M.J., Aubrecht J.;
RT   "The utility of DNA microarrays for characterizing genotoxicity.";
RL   Environ. Health Perspect. 112:420-422(2004).
//