Cell line name |
ELF-153 |
Synonyms |
Elf-153; ELF153 |
Accession |
CVCL_2031 |
Resource Identification Initiative |
To cite this cell line use: ELF-153 (RRID:CVCL_2031) |
Comments |
Part of: LL-100 blood cancer cell line panel. Characteristics: CSF2 dependent. Doubling time: 36 hours (PubMed=7488550; PubMed=7519473); ~40-60 hours (DSMZ=ACC-693). Omics: Deep exome analysis. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371. |
HLA typing |
Source: DSMZCellDive=ACC-693
Class I | HLA-A | A*01:01:01,02:01:01 | HLA-B | B*08:01:01,35:01:01 | HLA-C | C*07:01:01,07:01:01 | Class II | HLA-DP | DPA1*01:03:01,02:01:01 | | DPB1*14:01:01,04:02:01 | HLA-DQ | DQB1*03:01:01,03:01:01 | HLA-DR | DRA*01:01:01,01:01:01 | | DRB1*09:01:02,11:01:01 |
|
Disease |
Adult acute myeloid leukemia (NCIt: C9154) Acute myeloid leukemia (ORDO: Orphanet_519) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Sex of cell |
Male |
Age at sampling |
41Y |
Category |
Cancer cell line |
STR profile |
Source(s): DSMZ=ACC-693; Technion Genomics Center
Markers:Amelogenin | X |
CSF1PO | 10 |
D1S1656 | 15.3,16 |
D2S441 | 11,14 |
D2S1338 | 18,25 |
D3S1358 | 17,18 (Technion Genomics Center) 18 (DSMZ=ACC-693) |
D5S818 | 11 |
D7S820 | 9,10 (DSMZ=ACC-693) 9.3 (Technion Genomics Center) |
D8S1179 | 12,13 |
D10S1248 | 13,14 |
D12S391 | 19 |
D13S317 | 8 |
D16S539 | 12,13 |
D18S51 | 12,15 |
D19S433 | 13,14.2 (Technion Genomics Center) 13,15 (DSMZ=ACC-693) |
D21S11 | 31,32.2 |
D22S1045 | 16 |
FGA | 19,23 |
Penta D | 12,13 |
Penta E | 12,14 |
TH01 | 6,9 |
TPOX | 8,11 |
vWA | 19 |
Run an STR similarity search on this cell line |
Publications | CLPUB00037 Freund M., Kleine H.-D., Lux E., Exeriede G., Hanauske A.-R., Herbst H., Vainchenker W., Schweigerer L., Fonatsch C., Poliwoda H. ELF-153: a novel cell line derived from a patient with acute myelofibrosis and AML. Blut 61:128-128(1990) PubMed=7519473; DOI=10.1182/blood.V84.4.1085.1085 Mouthon M.-A., Freund M., Titeux M., Katz A., Guichard J., Breton-Gorius J., Vainchenker W. Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis. Blood 84:1085-1097(1994) PubMed=7488550; PMCID=PMC1997200 Hassan H.T., Hanauske A.-R., Lux E., Kleine H.-D., Freund M. A new fibroblast growth stimulating activity from the human megakaryoblastic leukaemia cell line ELF-153: in vitro and in vivo findings. Int. J. Exp. Pathol. 76:361-367(1995) DOI=10.1016/B978-0-12-221970-2.50457-5 Drexler H.G. The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001) PubMed=16408098; DOI=10.1038/sj.leu.2404081 Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G. JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders. Leukemia 20:471-476(2006) PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646 Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K.G., Uphoff C.C., Drexler H.G. The LL-100 panel: 100 cell lines for blood cancer studies. Sci. Rep. 9:8218-8218(2019) |
Cross-references |
Cell line collections (Providers) |
DSMZ; ACC-693
|
Cell line databases/resources |
DSMZCellDive; ACC-693
|
Biological sample resources |
BioSample; SAMN03473443
|
Encyclopedic resources |
Wikidata; Q54832241
|
Gene expression databases |
ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
|
Polymorphism and mutation databases |
Cosmic; 787427
Cosmic; 975245
Cosmic; 1012064
Cosmic; 1281310
Cosmic; 1465954
Cosmic; 2306197
|
Entry history |
Entry creation | 04-Apr-2012 |
Last entry update | 10-Sep-2024 |
Version number | 21 |
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