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Cellosaurus DT40-RASGRP1(-/-) (CVCL_1U38)

[Text version]
Cell line name DT40-RASGRP1(-/-)
Synonyms GRP1^(-)DT40
Accession CVCL_1U38
Resource Identification Initiative To cite this cell line use: DT40-RASGRP1(-/-) (RRID:CVCL_1U38)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; UniProtKB; A0A8V0ZL53; RASGRP1.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line
Publications

PubMed=14676298; DOI=10.1084/jem.20031547
Oh-hora M., Johmura S., Hashimoto A., Hikida M., Kurosaki T.
Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling.
J. Exp. Med. 198:1841-1851(2003)

Cross-references
Cell line collections (Providers) RCB; RCB1863
Cell line databases/resources CLO; CLO_0051496
Encyclopedic resources Wikidata; Q54831530
Entry history
Entry creation08-Jul-2015
Last entry update30-Jan-2024
Version number10