Cellosaurus cell line SK-MEL-457 (CVCL

Cross-references
Cell line name	SK-MEL-457
Synonyms	SK-Mel-457
Accession	CVCL_1T91
Resource Identification Initiative	To cite this cell line use: SK-MEL-457 (RRID:CVCL_1T91)
Comments	From: Memorial Sloan Kettering Cancer Center; New York; USA.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=24576830).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625; PMCID=PMC4005042 Nissan M.H., Pratilas C.A., Jones A.M., Ramirez R., Won H., Liu C.-L., Tiwari S., Kong L., Hanrahan A.J., Yao Z., Merghoub T., Ribas A., Chapman P.B., Yaeger R.D., Taylor B.S., Schultz N., Berger M.F., Rosen N., Solit D.B. Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence. Cancer Res. 74:2340-2350(2014)
Cell line databases/resources	cancercelllines; CVCL_1T91
Encyclopedic resources	Wikidata; Q54954228
Entry history
Entry creation	08-Jul-2015
Last entry update	19-Dec-2024
Version number	10