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Cellosaurus DM12 [Human OCSCC] (CVCL_1Q83)

[Text version]
Cell line name DM12 [Human OCSCC]
Accession CVCL_1Q83
Resource Identification Initiative To cite this cell line use: DM12 [Human OCSCC] (RRID:CVCL_1Q83)
Comments Problematic cell line: Contaminated. Parent cell line (Tu 167) has been shown to be a UM-SCC-1 derivative (PubMed=21868764).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00397.
Population: Caucasian.
Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Disease Floor of mouth squamous cell carcinoma (NCIt: C4041)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4912 (Tu 167)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO10,11,12,14
D5S8189,11,13
D7S8208,9,12
D13S3178,11,13
D16S5399,12,13
TH016,7
TPOX8,11
vWA15,18,20

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=16978912; DOI=10.1016/j.oraloncology.2006.04.016
Kupferman M.E., Patel V., Sriuranpong V., Amornphimoltham P., Jasser S.A., Mandal M., Zhou G., Wang J., Coombes K.R., Multani A.S., Pathak S., Gutkind J.S., Myers J.N.
Molecular analysis of anoikis resistance in oral cavity squamous cell carcinoma.
Oral Oncol. 43:440-454(2007)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

Cross-references
Biological sample resources BioSample; SAMN03151988
Encyclopedic resources Wikidata; Q54831196
Entry history
Entry creation08-Jul-2015
Last entry update02-May-2024
Version number15