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Cellosaurus PC-MDS (CVCL_1Q81)

[Text version]
Cell line name PC-MDS
Accession CVCL_1Q81
Resource Identification Initiative To cite this cell line use: PC-MDS (RRID:CVCL_1Q81)
Comments Problematic cell line: Contaminated. Shown to be a K-562 derivative (PubMed=19344951).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00379.
Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=17350682; DOI=10.1016/j.leukres.2007.01.012
Bogdanovic G., Jurisic V., Kraguljac N., Mrdjanovic J., Jakimov D., Krtolica K., Krajnovic M., Magic Z., Stojiljkovic B., Andrijevic L., Srdic T., Baltic M., Popovic S.
Characteristics of novel myeloid precursor cell line, PC-MDS, established from a bone marrow of the patient with therapy-related myelodysplastic syndrome.
Leuk. Res. 31:1097-1105(2007)

PubMed=17917092; DOI=10.1007/s12032-007-0031-y
Bogdanovic G., Jakimov D., Stojiljkovic B., Jurisic V.
The cell growth, morphology and immunocytochemistry of novel cell line established from a bone marrow of the patient with therapy-related myelodysplastic syndrome, entitled PC-MDS.
Med. Oncol. 24:419-424(2007)

PubMed=19344951; DOI=10.1016/j.leukres.2009.03.005
Drexler H.G., Dirks W.G., MacLeod R.A.F.
Many are called MDS cell lines: one is chosen.
Leuk. Res. 33:1011-1016(2009)

Biological sample resources BioSample; SAMN03151810
Encyclopedic resources Wikidata; Q54938512
Entry history
Entry creation08-Jul-2015
Last entry update29-Jun-2023
Version number19